What Is goBHB? Full Guide to Exogenous BHB

What is gobhb full guide to exogenous bhb ketone labs gobhb ketones 001

Introduction to goBHB

Beta-Hydroxybutyrate (BHB) is a naturally occurring ketone body, a potent cellular fuel traditionally produced by the liver during states of fasting, carbohydrate restriction, or ketogenic diets. goBHB® by Ketone Labs is a patented, high-quality exogenous form of BHB. Unlike endogenous ketones, goBHB provides immediate and accessible ketones without the dietary challenges of sustained ketosis.

Understanding the Molecule BHB

BHB is one of the three main ketone bodies—alongside acetoacetate (AcAc) and acetone—that serve as alternative energy sources for the brain, heart, and skeletal muscles during periods of glucose scarcity. BHB is uniquely efficient: it rapidly crosses the blood-brain barrier, accumulating in brain tissue, and provides significantly more energy per molecule compared to glucose.

How goBHB Works in the Body

goBHB supplementation delivers exogenous ketones that can immediately elevate blood ketone levels. These ketones bypass the traditional ketogenic pathway (fat oxidation in the liver) and directly provide the body and brain with a clean and efficient energy source. Unlike glucose, goBHB metabolism generates minimal reactive oxygen species (ROS), reducing oxidative stress and inflammation at the cellular level.

goBHB vs. Glucose: Superior Cellular Fuel

goBHB offers several metabolic advantages compared to glucose:

Gobhb vs glucose bhb superior cellular fuel 001
  • Efficiency: Produces ATP (adenosine triphosphate), the body’s primary energy currency, more efficiently than glucose per unit of oxygen consumed.
  • Reduced Oxidative Stress: Metabolism of BHB generates 46 times fewer harmful ROS compared to glucose, reducing cellular damage.
  • Independent of Insulin: Unlike glucose, BHB does not require insulin to enter cells, making it an ideal energy source for metabolic health.

Key Benefits of goBHB

goBHB supplementation provides a variety of well-documented health and performance benefits:

Cellular Energy and Metabolic Efficiency

  • Immediate and sustained energy for mental clarity and physical endurance.
  • Enhanced mitochondrial ATP production with less oxidative stress.

Cognitive Enhancement

  • Improves working memory, executive function, and overall brain performance.
  • Stimulates brain-derived neurotrophic factor (BDNF), promoting neuronal health and plasticity.

Metabolic Health

  • Supports insulin sensitivity, regulates blood sugar, and aids in weight management through appetite suppression and enhanced fat burning.

Athletic Performance

  • Extends physical endurance and accelerates recovery by providing an efficient and clean energy source without the spikes and crashes associated with glucose or caffeine-based supplements.

Hydration and Electrolyte Balance

  • goBHB electrolytes promote superior hydration by regulating fluid balance and enhancing electrolyte absorption, beneficial for athletic recovery and overall wellness.

Stress and Anxiety Reduction

  • Reduces normal stress and anxiety levels by modulating neurotransmitter pathways and mitigating the physiological effects of chronic stress.

Sleep Quality and Recovery

Emerging research also links BHB supplementation to improved sleep. Studies suggest that elevated ketone levels can enhance deep sleep stages by modulating GABAergic activity and reducing nighttime cortisol levels. 

Users report better sleep efficiency, fewer mid-night awakenings, and improved morning alertness when supplementing with goBHB—especially when taken in the evening alongside balanced electrolytes. This makes goBHB a practical tool for recovery, circadian alignment, and overall sleep hygiene.

Clinical Evidence and Efficacy

Research consistently supports goBHB’s effectiveness:

  • Weight Management: Clinical trials show that daily supplementation with goBHB can significantly reduce waist circumference and improve body composition without dietary restrictions.
  • Improved Cognition: Studies reveal that BHB supplementation enhances cognitive performance and reduces anxiety, improving quality of life metrics.
  • Metabolic Biomarkers: Evidence indicates that goBHB improves insulin sensitivity, reduces LDL cholesterol, and supports healthy blood glucose management.

Why Choose Exogenous Ketones?

Maintaining ketosis through dietary means can be difficult. goBHB provides a practical alternative, allowing individuals to access the benefits of ketones without the strict adherence required by ketogenic diets or fasting protocols. Exogenous ketones also enable precise dosing and timing, optimizing metabolic health, cognitive performance, and athletic recovery when it matters most.

goBHB as the Fourth Macronutrient

Emerging scientific literature positions BHB as the “fourth macronutrient” alongside carbohydrates, fats, and proteins. BHB provides direct, efficient ATP generation, making it uniquely valuable for cellular metabolism and overall health. This perspective underscores goBHB’s role not merely as a dietary supplement but as a fundamental nutrient supporting long-term metabolic flexibility and energy homeostasis.

Conclusion

goBHB by Ketone Labs is more than just a supplement—it represents a fundamental shift in how we view energy metabolism. With its unmatched efficiency, cognitive enhancement properties, and wide-ranging metabolic benefits, goBHB sets a new standard for cellular fuel. Whether optimizing physical performance, improving metabolic health, or enhancing cognitive function, goBHB offers scientifically validated results.


Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Ketone Labs Partners with Simpson Labs: A Game-Changing Alliance for goBHB Innovation​

Ketone labs & simpson labs partnership

Ketone Labs Partners with Simpson Labs: A Game-Changing Alliance for goBHB Innovation

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By: Marc Lobliner, President – Ketone Labs

This past week marked a major milestone in the future of exogenous ketones and premium supplementation. I had the pleasure of visiting Simpson Labs in Valencia, California, alongside our Account Executive, David Barnes. We spent the day collaborating with industry veterans Donald Grace and Eric Simpson, diving deep into formulation strategy, application potential, and manufacturing capabilities.

We capped the day with a Dodgers game—and while the home team didn’t pull off the win, the real victory came in the form of a powerful new partnership that will benefit dozens of brands looking to bring cutting-edge, goBHB-powered formulas to life.

 

Simpson Labs has long been recognized as a gold standard in contract manufacturing. From powders to capsules to stick packs, they deliver world-class products backed by rigorous quality control and unmatched customer service. Their commitment to innovation and transparency aligns perfectly with our mission at Ketone Labs.

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Through this collaboration, Simpson Labs will gain priority access to goBHB®—the most versatile and clinically validated exogenous ketone on the market. This positions them to offer their clients superior fat-burning, cognitive-enhancing, and endurance-boosting formulas that meet the rising demand for real, research-backed ingredients.

At Ketone Labs, we’re more than just an ingredient supplier—we’re your partner in building brands that perform. With Simpson Labs on board, our ability to support brands from ideation to finished product just got even stronger.

 

Stay tuned. The goBHB wave is only getting bigger—and with Simpson Labs in our corner, we’re ready to take it to the next level.

The Ultimate Ketone Breakdown with Dr. Ben Bikman and Marc Lobliner

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  • The Ultimate Ketone Breakdown with Dr. Ben Bikman and Marc Lobliner

By Marc Lobliner, IFBB Pro

I’ve talked about ketones for years—but this podcast with Dr. Ben Bikman dives deep into the real science behind why ketones aren’t just another fitness buzzword. They’re a biological fuel source your body was designed to use. And if you’re not tapping into that power, you’re leaving performance, clarity, and longevity on the table.

Let’s break it down.

 


Glucose vs. Ketones: What Fuels You Best?

Most of us are running on sugar—glucose. But your body was made to run more efficiently on ketones, especially beta-hydroxybutyrate (BHB). Dr. Bikman explains that while glucose spikes insulin and can drive inflammation, ketones are clean fuel. They don’t trigger insulin, and they help the body become metabolically flexible—able to switch between fat and glucose for energy.

Why does this matter? Because high insulin isn’t just about diabetes. It’s about brain fog, fat gain, and chronic disease. According to Bikman, over 93% of Americans have some form of metabolic dysfunction, often driven by constant carb fueling.


Ketones and Brain Power

This one hit home. Dr. Bikman shared how the brain prefers ketones over glucose in many scenarios, especially under stress or during fasting. In studies, BHB improves mental clarity, memory recall, and even mood.

There’s a reason Alzheimer’s is being called Type 3 Diabetes—it’s rooted in insulin resistance in the brain. Ketones bypass that broken system and deliver the energy your neurons need.

Dr. Bikman cited research showing ketones increase BDNF (Brain-Derived Neurotrophic Factor), which supports learning, memory, and even neuroprotection. In short: ketones help your brain stay sharp and protected against aging.


BHB: The Body’s Super Fuel

BHB is more than just an energy molecule—it’s a signaling molecule. That means it tells your body to do things like:

  • Reduce inflammation (by blocking the NLRP3 inflammasome)

  • Burn more fat

  • Boost mitochondrial function

  • Improve muscle preservation during caloric deficits or fasting

Dr. Bikman emphasized that BHB works independent of diet. You don’t have to go strict keto to see benefits—exogenous ketones can raise BHB levels in your blood within 30 minutes and start shifting your metabolism toward fat oxidation.


Performance and Recovery: Ketones in the Gym

I’ve personally seen the benefits of using ketones in training. What Dr. Bikman explains is that ketones provide a stable, long-burning fuel that doesn’t crash. That means more consistent energy during lifts, endurance sessions, and even during tournaments or long competitions.

Research cited in the podcast shows that ketone supplementation improved recovery markers, reduced perceived exertion, and preserved lean muscle mass during cut phases.


Ketones and Longevity

One of the most exciting parts of this conversation was the longevity angle. Elevated ketones are associated with increased autophagy (cellular cleanup), reduced oxidative stress, and better insulin sensitivity—all markers of extended lifespan.

As Dr. Bikman pointed out, some of the longest-living populations in the world regularly undergo periods of fasting or carbohydrate restriction—naturally raising ketone levels.


Why goBHB Matters

Not all ketones are created equal. goBHB® is the gold standard for exogenous ketones—it’s bioidentical, clinically studied, and fast-acting. You can find it in products ranging from fat burners to brain health to endurance support.

It’s what I trust in my own supplement stack and in formulas we develop, because the science is there—and people feel the difference.


Final Thoughts

We’re only scratching the surface of what ketones can do. Whether your goal is fat loss, brain power, or living longer and stronger—ketones are the missing link most people are ignoring.

You don’t need to go zero-carb. You just need to use the fuel your body was built for.

Watch the full conversation with Dr. Ben Bikman here: https://youtu.be/TywW4F1cRbg

 

If you want to feel the difference, try a product with goBHB and track your energy, focus, and recovery. You’ll never go back.

Therapeutic Ketosis for Heart Failure

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Therapeutic Ketosis for Heart Failure

By: Marc Lobliner, IFBB Pro

A recent state‑of‑the‑art review published in the Journal of Cardiac Failure (Kodur et al., 2025) shows that failing hearts naturally increase ketone oxidation as a survival mechanism for energy production. Small clinical trials have demonstrated that supplementing with ketones like beta-hydroxybutyrate (BHB) can improve heart function in patients with heart failure. The review highlights promising results for exogenous ketones in boosting cardiac output, stroke volume, and ejection fraction—metrics directly tied to heart performance.


Key Insights from the Review

Failing hearts suffer from an energy crisis. Normally, the heart burns glucose and fatty acids. But in heart failure, those pathways become inefficient. As a result, the heart shifts toward burning ketones, which are a more efficient and clean fuel.

The most accessible and impactful ketone for this purpose is beta-hydroxybutyrate (BHB). Studies now show that even in the most compromised hearts, infusions of BHB lead to immediate improvements in pumping capacity, oxygen use, and energy output.

These trials show that therapeutic ketosis—whether induced via diet or supplementation—can play a major role in improving cardiac performance.


Additional Clinical and Mechanistic Evidence

Acute Hemodynamic Boost
Research demonstrates that infusion of 3-OHB in heart failure patients led to a 40% increase in cardiac output, a 20 mL improvement in stroke volume, and an 8% increase in ejection fraction. This was achieved without a loss in cardiac efficiency or increased oxygen demand.

Ketones as Preferred Fuel
In failing hearts, up to 16% of the energy production (ATP) can come from ketones. This shift in metabolism suggests that the heart prefers ketones when under stress, and providing them exogenously makes a real difference in performance.

Anti-Inflammatory and Remodeling Effects
BHB has been shown to inhibit the NLRP3 inflammasome—a driver of chronic inflammation and tissue scarring in heart failure. By reducing inflammation, BHB may also limit myocardial fibrosis and support cardiac remodeling.

Endothelial and Vascular Support
Ketones have demonstrated an ability to support endothelial cell growth and blood vessel formation, which may improve circulation and nutrient delivery to the heart muscle itself.

 

Alignment with SGLT-2 Inhibitor Research
SGLT-2 inhibitors like empagliflozin, known for improving heart failure outcomes, also raise ketone levels. Many researchers believe this increase in circulating BHB is one of the reasons behind their success.

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The Role of goBHB Supplementation

goBHB is a patented form of exogenous BHB that offers all the metabolic benefits of therapeutic ketosis—without needing a restrictive ketogenic diet. It rapidly elevates blood ketone levels into the 1 to 3 mM range, which mirrors what’s seen in the successful heart failure trials.

For individuals recovering from cardiovascular strain, dealing with heart failure symptoms, or simply looking to improve endurance and energy metabolism, goBHB offers a promising and accessible tool. It provides fuel, reduces inflammation, and may enhance the overall metabolic flexibility of the heart.


Take-Home Message

The new research—including the 2025 review by Kodur et al.—shows that goBHB isn’t just a performance supplement or keto hack. It’s a powerful metabolic fuel with clinically relevant benefits for cardiovascular health.

For patients with heart failure, BHB helps the heart recover some of its lost function. For athletes and high-performers, it can enhance endurance and recovery. For those looking to support long-term heart health, it offers an additional tool in the metabolic arsenal.

With its ability to improve cardiac energy efficiency, reduce inflammation, and support vascular integrity, goBHB stands at the forefront of the next wave of heart health support—grounded in clinical science, not hype.


References

 

  • Kodur et al., Therapeutic Ketosis for Heart Failure: A State-of-the-Art Review. Journal of Cardiac Failure, 2025. PubMed ID: 40043832

  • Nielsen et al., Hemodynamic Effects of Ketone Bodies in Heart Failure with Reduced Ejection Fraction. Circulation, 2019.

  • Matsuura et al., Ketones and the Heart: Metabolic Principles. Circulation Research, 2023.

  • Frontiers in Pharmacology: Beta-hydroxybutyrate and Heart Function, 2024.

Creatine and BHB: The Ultimate Performance Stack Backed by Science

Creatine and BHB: The Ultimate Performance Stack Backed by Science

Why This Dual-Fuel System Could Be the Biggest Breakthrough in Fitness and Brain Health Since Protein

By Marc Lobliner, IFBB Pro

Creatine has dominated the performance supplement space for decades. BHB (beta-hydroxybutyrate), a powerful ketone body, has risen rapidly as a cognitive and metabolic enhancer. But combine the two? That’s where things get groundbreaking. Backed by over 20 years of sports nutrition research and dozens of peer-reviewed studies, this combo delivers an unmatched synergy of explosive strength, endurance, fat burning, cognitive sharpness, and cellular recovery.

At Ambrosia, we’ve built our reputation on blending cutting-edge science with time-tested ingredients—and the creatine + BHB synergy is our biggest breakthrough yet. This isn’t hype. It’s science-backed, result-proven, and athlete-tested.

And the best part? We’ve made it easier than ever to tap into this dual-fuel advantage with goBHB®, our premium exogenous ketone formula designed to elevate performance, sharpen mental focus, and support your fat-loss goals without the need for a strict ketogenic diet. goBHB® delivers fast-acting, clean-burning ketones that work synergistically with creatine to amplify endurance, buffer fatigue, and accelerate recovery.

Whether you’re deep in contest prep, chasing PRs, or battling brain fog, goBHB® provides the metabolic edge you need to dominate every session. Add it to your pre-workout stack or take it solo for all-day cognitive support. The future of supplementation isn’t either/or—it’s BOTH.


The Science Behind the Stack: Creatine + BHB = Total Cellular Fuel

Creatine helps regenerate ATP via the phosphocreatine system, supporting fast, anaerobic energy production. According to a 2017 meta-analysis in Journal of Strength and Conditioning Research, creatine increases strength and lean body mass significantly (Kreider et al., 2017). It’s also been shown to reduce exercise-induced muscle damage and inflammation (Rawson & Volek, 2003).

BHB, on the other hand, is an endogenous ketone body that fuels oxidative ATP production in mitochondria. In a 2009 study published in Bioscience, Biotechnology, and Biochemistry, acetic acid and BHB were linked to improved fat loss and insulin sensitivity (Kondo et al., 2009). BHB also acts as a signaling molecule—activating genes linked to longevity, stress resilience, and mitochondrial function (Shimazu et al., 2013).

Together, they cover both anaerobic and aerobic energy systems. Creatine powers you through sprints and heavy sets, while BHB keeps your engine running clean, even during caloric restriction or long-duration efforts.


Cognitive Gains: Boost Brain Power and Resilience

Creatine increases brain phosphocreatine, enhancing ATP availability in neurons. This has been linked to improved memory and intelligence test performance in older adults (Avgerinos et al., 2018). Creatine also reduces neuronal oxidative stress and supports neurotransmitter synthesis (Rae et al., 2003).

BHB readily crosses the blood–brain barrier and improves mental clarity, raises brain-derived neurotrophic factor (BDNF), and reduces neuroinflammation. In cell studies, BHB upregulated BDNF and protected glial cells from oxidative damage (Marosi et al., 2016).

Combined, they may improve outcomes under stress (e.g. sleep deprivation or hypoxia), enhancing memory, decision-making, and mental stamina. One review found creatine improved cognitive performance during mental fatigue, while ketones like BHB support sustained focus (Dolan et al., 2019).


Muscle Performance and Endurance: Max Out Every Session

Creatine is well-known to increase strength and power output by 10–20% in high-intensity training (Kreider et al., 2017). It enhances recovery and reduces inflammatory markers post-exercise (Cooke et al., 2009).

BHB improves mitochondrial function, shifts substrate use toward fat, and extends time to exhaustion. A 2016 study in Cell Metabolism showed exogenous ketones improved endurance and metabolic efficiency in athletes (Cox et al., 2016).

In rodent models, creatine + BHB improved rotarod performance (motor coordination), grip strength, and fatigue resistance beyond either alone. Human athletes report increased stamina, quicker recovery, and reduced soreness.


Lean Gains and Faster Recovery

  • Creatine boosts glycogen storage (Robinson et al., 1999), enhances protein synthesis via mTOR, and reduces markers of muscle breakdown.

  • BHB spares muscle protein during fasted states, enhances insulin sensitivity, and improves fat oxidation (Stubbs et al., 2017).

Together, the stack promotes lean mass retention while reducing fat accumulation. BHB’s anti-inflammatory and antioxidant effects support a more anabolic environment.


The Biochemical Synergy

  1. Dual Energy Systems:

    • Creatine → Immediate ATP buffer via phosphocreatine

    • BHB → Long-term ATP via mitochondrial oxidation

  2. Signaling Boost:

    • AMPK activation (BHB) → Fat oxidation, autophagy

    • mTOR activation (Creatine) → Protein synthesis, hypertrophy

  3. Cellular Resilience:

    • HDAC inhibition (BHB) → Gene expression for antioxidant enzymes (e.g., MnSOD, catalase)

    • Increased mitochondrial biogenesis and function (both)

  4. Anti-Inflammatory:

    • BHB inhibits NLRP3 inflammasome (Youm et al., 2015)

    • Creatine reduces TNF-α and CRP post-exercise (Rahimi et al., 2017)


Organs and Systems That Benefit

  • Brain: Neuroprotection, enhanced cognition, mood support

  • Muscle: Strength, hypertrophy, endurance

  • Heart: Improved fuel use in heart failure models (Lopaschuk et al., 2016)

  • Immune: Balanced macrophage polarization (BHB via GPR109A, Creatine via T-cell energetics)

  • Metabolism: Fat loss, improved lipid profile, glucose control


Conclusion: The Smartest Stack in Sports Nutrition

This isn’t just a trendy pairing—it’s a scientifically validated breakthrough. The synergy between creatine and BHB creates a metabolic environment optimized for peak performance, rapid recovery, lean muscle growth, and brain health.

If you’re ready to experience the true power of this dual-fuel system, start with goBHB®. It’s keto-friendly, stimulant-free, and engineered to deliver sustained energy, mental clarity, and fat-burning potential whether you’re in the gym or grinding through your day.

We’re not reinventing the wheel. We’re giving it rocket fuel.

Citations:

  • Kreider et al., J Strength Cond Res, 2017

  • Kondo et al., Biosci Biotechnol Biochem, 2009

  • Marosi et al., Neuropharmacology, 2016

  • Cox et al., Cell Metabolism, 2016

  • Rae et al., Proc Biol Sci, 2003

  • Avgerinos et al., Exp Gerontol, 2018

  • Youm et al., Nat Med, 2015

  • Stubbs et al., Front Physiol, 2017

  • Cooke et al., Int J Sports Nutr, 2009

  • Rahimi et al., J Sports Med Phys Fitness, 2017

  • Robinson et al., Med Sci Sports Exerc, 1999

  • Lopaschuk et al., Circulation Research, 2016

  • Dolan et al., Nutrients, 2019

Build the Perfect Pre-Workout Using goBHB — With and Without Stimulants​

Build the Perfect Pre-Workout Using goBHB — With and Without Stimulants

By Marc Lobliner, IFBB Pro


Your pre-workout determines your performance.

It’s that simple. What you take before you train has a direct impact on how intensely you can push, how long you can last, and how quickly you recover. Over the past 20 years, I’ve tested nearly every pre-workout ingredient on the planet — from caffeine and citrulline to nootropics and adaptogens. But one ingredient that has consistently stood out — and remains criminally underused — is goBHB, a bioavailable exogenous ketone.

goBHB isn’t just another energy ingredient. It’s a fuel source. A mental clarity enhancer. A performance optimizer. And for a significant portion of the training population — particularly the 30%+ of people who hit the gym after 5 p.m. — it’s the perfect solution for maximizing workouts without compromising sleep or recovery.

This article is going to break down how goBHB works, why it belongs in your pre-workout, and how to build two elite-level pre-workout stacks using it — one with stimulants and one without.


What is goBHB?

goBHB stands for beta-hydroxybutyrate, a naturally occurring ketone body that your liver produces during periods of fasting or carbohydrate restriction. It’s one of your body’s most efficient fuel sources — delivering more ATP per molecule than glucose — and it’s especially valuable when blood sugar is low or steady.

goBHB is used in supplements as a ketone salt — bonded with minerals like sodium, calcium, or magnesium — to increase its bioavailability and absorption. Once ingested, it quickly elevates ketone levels in the blood, providing your brain and muscles with clean, direct energy.

Unlike caffeine, which stimulates the central nervous system to create a sense of energy, goBHB actually fuels your cells. That means no jittery feeling, no crash, and no adrenal fatigue. Just stable, powerful energy that lasts.


Why goBHB Belongs in Your Pre-Workout

Most people think of pre-workout formulas in terms of three categories: stimulants for energy, pump agents for blood flow, and nootropics for focus. But what they’re missing is the fuel source. It’s like building a high-performance car with the best engine, tires, and electronics — but skipping the fuel.

goBHB fills that gap. It’s a clean-burning fuel that works synergistically with other ingredients to enhance performance across the board.

Here’s what makes goBHB a cornerstone pre-workout ingredient:

1. Clean Cellular Energy

goBHB bypasses the traditional glycolysis pathway (which breaks down glucose) and enters the mitochondria directly, where it produces ATP — your cells’ energy currency — more efficiently than carbs. This results in more sustained energy and less metabolic waste.

2. Mental Clarity and Focus

goBHB has been shown to increase levels of GABA, a neurotransmitter that promotes calm, focus, and mental sharpness. This is especially beneficial for late-day workouts when mental fatigue sets in.

3. Appetite Control

If you train fasted or during a cut, goBHB can help curb hunger and stabilize blood sugar, allowing you to train harder without distraction or cravings.

4. No Crash, No Jitters

Because it’s not a stimulant, goBHB doesn’t spike your heart rate or cause a post-workout crash. This makes it ideal for late-night lifters or anyone trying to avoid caffeine-related side effects.


The Late-Day Training Dilemma

Over 30 percent of people train after 5 p.m. That’s a huge portion of the fitness world — from busy professionals to parents to students — who have to work around their daily schedules.

The problem? Most pre-workouts on the market are stimulant-loaded. They’re packed with caffeine, yohimbine, and other hard-hitting ingredients that may boost performance temporarily but wreck your sleep hours later. And let’s be honest — poor sleep undermines everything you do in the gym.

goBHB is the solution. It gives you the energy, clarity, and performance you need — without interfering with your ability to wind down post-workout.

In fact, the elevated ketone levels from goBHB can actually support better sleep by promoting GABA activity in the brain, reducing cortisol levels, and stabilizing blood glucose — all factors associated with improved sleep onset and depth.

So, you train hard. You perform. And then you rest. That’s how you recover and grow.


The Stimulant-Based goBHB Pre-Workout Formula

For those who train earlier in the day, are less sensitive to caffeine, or want maximum drive and alertness — this version stacks goBHB with classic performance-enhancing ingredients.

Ingredients per serving:

  • goBHB – 6g

  • L-Citrulline – 6 to 8g

  • Beta-Alanine – 3.2g

  • Caffeine Anhydrous – 250 to 300mg

  • Alpha-GPC – 300mg

  • Theobromine – 100mg

  • Himalayan Sea Salt – 500mg

  • Taurine – 1g

  • Tyrosine – 1g

How It Works:

  • goBHB provides clean fuel, sparing muscle glycogen and keeping energy steady.

  • Caffeine and Theobromine stimulate the central nervous system, increasing motivation, focus, and pain threshold.

  • Alpha-GPC and Tyrosine enhance cognitive function, making you more alert and focused under load.

  • L-Citrulline and Beta-Alanine improve blood flow and endurance.

  • Electrolytes and Taurine support hydration and muscle contractions.

Together, this stack hits all three performance pillars: fuel, focus, and force. You’ll feel energized, dialed-in, and strong from your first warm-up set to your last working rep.


The Non-Stimulant goBHB Pre-Workout Formula

This version is built for those training in the evening, during a deload, or while cycling off stimulants. It offers all the performance without the nervous system load.

Ingredients per serving:

  • goBHB – 8g

  • L-Citrulline – 8g

  • Betaine Anhydrous – 2.5g

  • Taurine – 2g

  • Nitrates (NO3-T) or Nitrosigine – 1.5g

  • Electrolyte blend – sodium, magnesium, potassium

  • Tyrosine – 1.5g

  • Acetyl-L-Carnitine (ALCAR) – 1g

How It Works:

  • goBHB provides rapid, sustained energy without stimulation.

  • L-Citrulline and Nitrates promote nitric oxide production, giving you powerful pumps and enhanced blood flow.

  • Betaine and Taurine increase strength and hydration.

  • Tyrosine and ALCAR sharpen focus and prevent mental fatigue.

  • Electrolytes keep your muscles firing optimally and prevent cramping.

This formula is ideal for fasted cardio, high-rep bodybuilding sessions, or any training block where sleep and recovery are a priority.


When to Use Which Version

Morning or mid-day sessions? Use the stimulant-based version. It’ll energize you, mentally and physically, and help drive performance without affecting your sleep later.

After-work or late-night lifts? Use the stimulant-free version with a higher dose of goBHB. You’ll still get the fuel, focus, and performance — but you’ll actually be able to relax when you’re done.

Fasted cardio or cutting phase? Either version works, but goBHB is especially helpful at suppressing appetite and preserving muscle while enhancing energy.


goBHB: The Missing Link in Performance Nutrition

Too many lifters are still relying on overhyped stimulant blends, mistaking artificial buzz for real performance. But peak training isn’t about how “hyped” you feel — it’s about how hard you can push, how long you can sustain it, and how quickly you bounce back.

goBHB fills the gap most pre-workouts ignore — true fuel. It’s a real energy substrate, not a trick. It fuels your cells, not just your senses. And it works for nearly every kind of athlete, in every kind of training environment.

The best part? It doesn’t compromise your recovery. In fact, by avoiding nervous system overload and improving neurotransmitter balance, it supports better rest and more efficient recovery — which leads to more consistent gains over time.


Final Thoughts

Building the perfect pre-workout isn’t about hype — it’s about execution. What you put in your body before you train has to work with your goals, not against them. And whether you’re chasing hypertrophy, strength, fat loss, or endurance, the foundation is always the same: consistent energy, sharp focus, and strong output.

goBHB delivers all of it.

Whether you’re stacking it with stimulants for a mid-morning lift or using it solo in a stim-free evening session, this ingredient gives you exactly what you need: fuel for your body, clarity for your mind, and support for your recovery.

It’s time to stop guessing and start building your pre-workout the right way.

goBHB®: The Future of Clean Energy – Why It Might Replace Caffeine in Your Next Drink

goBHB®: The Future of Clean Energy – Why It Might Replace Caffeine in Your Next Drink

By: Marc Lobliner, IFBB Pro

Let me be blunt: caffeine is a gift — but it’s also a crutch. We live in a society where energy drinks are being chugged like water, yet burnout, anxiety, and energy crashes are worse than ever. The irony is hard to miss.

As someone who’s lived and breathed the supplement industry for decades, I’ve seen every energy ingredient come and go. Jitter bombs. Pixie-dusted herbs. Mega-stim cocktails that jack you up and leave you shattered. But every once in a while, something comes along that actually changes the game.

And right now, goBHB® is that something.


What Is goBHB®?

goBHB stands for Beta-Hydroxybutyrate, a type of ketone body that your body naturally produces during periods of low carbohydrate intake, fasting, or intense endurance training. But you don’t need to be on a keto diet to benefit from it.

goBHB is a bio-identical, exogenous ketone salt. That means your body sees it as energy — clean energy — and uses it immediately. Unlike caffeine, which stimulates your nervous system, goBHB literally fuels your cells. It’s actual energy, not borrowed energy.


Why goBHB Works — Even If You’re Not Keto

One of the biggest misconceptions is that goBHB is only useful if you’re on a ketogenic diet.

Wrong.

goBHB offers benefits for anyone — and here’s why:

  • Dual-fuel advantage: Your body can use both glucose and ketones for energy. Adding goBHB into the mix allows your brain and muscles to run cleaner and longer, without the insulin spikes and crashes associated with sugar or caffeine.

  • Mitochondrial efficiency: BHB is used by the mitochondria (your cellular engines) more efficiently than glucose, creating more ATP per molecule. Translation: more real energy, less waste, zero jitters.

  • Cognitive boost: The brain loves ketones. In fact, research shows BHB may improve focus, clarity, and memory — without overstimulating the central nervous system like caffeine does.

  • No tolerance buildup: Caffeine tolerance builds fast. goBHB? Not so much. You can use it daily without needing to up the dose just to feel “normal.”

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Why goBHB Is Perfect for Energy Drinks

The current energy drink market is dominated by caffeine, taurine, and sugar (or sugar alcohols that tear up your gut). But the consumer is getting smarter. People want functional, clean, and sustainable energy.

Here’s how goBHB fits the bill:

  • Stable energy release: No roller-coaster crash, no heart palpitations.

  • Great flavoring potential: Modern flavor systems hide the saltiness.

  • Synergistic with small caffeine doses: Want a mild stim? Pair 50mg caffeine with 6g goBHB — perfect energy curve.

  • Nootropic effect: Feeds your brain for sharper focus and productivity.

  • Craving control: Reduces hunger and sweet cravings, making it perfect for dieters.

Imagine sipping an energy drink that doesn’t make you sweat, doesn’t wreck your sleep, and actually helps you think clearly.


Rev7 Energy: Proof That goBHB Works

Don’t just take my word for it — look at Rev7 Energy.

Built around goBHB as the star ingredient, Rev7 delivers energy without compromise. Consumers report clean, jitter-free fuel, sharper focus, and zero crash. It’s become the go-to for those sick of being overstimulated and underproductive.

In fact, Rev7 is gaining rapid traction in both retail and online spaces. Athletes, entrepreneurs, parents, students — the feedback is consistent: it works, and it feels good.

That’s the real-world proof we’ve been waiting for.


Real-World Use Cases

Here’s where goBHB truly shines:

  • Early morning focus without nervous energy

  • Afternoon crashes: Replace that second coffee with BHB and skip the slump

  • Fasted training: goBHB preserves muscle, fuels endurance, and enhances recovery

  • Students and professionals: Laser focus for hours without burnout

  • Entrepreneurs and parents (aka Superdads): Clean energy to power through chaotic days

As someone who trains, runs companies, raises three amazing kids, and lives by performance — I don’t have time to crash. That’s why I now reach for goBHB first.


Is goBHB Safe? What Does the Research Say?

In short: Yes, and it’s clinically validated.

Studies on BHB salts show:

  • Improved cognitive performance and mental clarity

  • Enhanced endurance capacity in trained athletes

  • Lower inflammatory markers such as IL-6 and TNF-alpha

  • Reduced perceived exertion during workouts

  • Improved insulin sensitivity and glycemic control

And unlike caffeine, goBHB doesn’t stimulate cortisol. It may actually help lower stress responses over time.


The Final Word

Look, I’m not anti-caffeine. I love a great pre-workout. I love a strong cup of coffee. But if you’re chasing sustainable energy, enhanced brain function, and smoother performance across the board, goBHB is the future.

It’s not just “keto fuel.” It’s human fuel.

If you’re a brand formulating the next-gen energy drink or a consumer looking to get off the caffeine rollercoaster, it’s time to look at what real cellular energy looks like.

 

And that, my friends, is goBHB.

goBHB® and BDNF: Fuel Your Brain Like It Deserves​

goBHB® and BDNF: Fuel Your Brain Like It Deserves

By: Marc Lobliner, IFBB Pro

Let’s talk about something most people overlook when it comes to energy, focus, and long-term performance: your brain. Not just how sharp it feels today, but how well it holds up over time. That’s where goBHB® comes in—and specifically, what it does to a molecule called BDNF.

This isn’t just another ingredient. This is real, clinical, bioavailable brain fuel—and it’s changing the game.

What the heck is BDNF—and why should you care?

BDNF stands for brain-derived neurotrophic factor. Think of it like Miracle-Gro for your brain. It helps grow new neurons, strengthens the ones you already have, and keeps your brain plastic—which means adaptable, sharp, and hard to break down.

Low BDNF levels? You’re looking at a higher risk of depression, anxiety, Alzheimer’s, poor memory, and honestly, just not feeling like yourself.

If you’re serious about your mental health, your focus, and long-term resilience, BDNF isn’t optional. It’s mandatory.

How goBHB® fires up BDNF naturally

Here’s where it gets real. goBHB® doesn’t just give you energy—it tells your body to be better. It gets into your bloodstream fast, crosses into the brain, and starts turning the right genes on. One of those genes? BDNF.

The magic happens through something called HDAC inhibition. That’s a fancy way of saying goBHB® unlocks your DNA to express the stuff that protects your brain—like antioxidant enzymes, mitochondrial repair pathways, and yes, BDNF.

It also increases PGC-1α, a coactivator that ramps up mitochondrial biogenesis. That’s more energy where it matters—inside your brain cells.

And we’re not just talking theory. This is backed by animal studies, human ketone research, and emerging data showing that when ketone levels go up, cognitive performance improves—and BDNF goes with it.

Why goBHB® is better than 1,3-butanediol—and it’s not even close

Look, a lot of companies out there are selling you 1,3-butanediol and calling it a ketone. It’s not. It’s an alcohol that your body has to convert into BHB—and that conversion takes ATP. That means it costs you energy to get any benefit.

Not only that, it can cause bloating, GI distress, and slow delivery. It’s not efficient, and it’s definitely not optimized for brain performance.

goBHB® is already in its active form. Your body doesn’t need to convert anything. It’s ready to use. That means faster results, cleaner performance, and real metabolic impact without the junk.

What this means for your brain and your performance

So what happens when your brain is running on clean fuel and BDNF is up?

You think faster. You focus longer. You adapt better to stress. You’re more resilient.

It’s like upgrading from a cheap gas station energy drink to rocket fuel—and your brain knows the difference.

This isn’t just for athletes. It’s for busy professionals, parents, students, anyone who wants to perform better and feel better—without the crash, the sugar, or the stimulants.

The proof is in performance

In 2024, both the men’s and women’s cross country teams at BYU won national championships while taking goBHB® daily. They used it for energy, for recovery, and for mental sharpness—and it delivered.

And it’s not just athletes. We’ve got professionals using this before meetings, students using it during finals, and everyday people using it to finally feel in control of their brain again.

Why goBHB® is leading the future of functional nutrition

Wellness is changing. People want real ingredients that do more. Not just hype. Not just caffeine.

They want metabolic health. Cognitive performance. Clean energy. And goBHB® checks all those boxes.

If you’re looking for the next evolution of performance fuel—something that supports your body and brain at the same time—goBHB® is it. You’re not just running on ketones. You’re running on momentum.

 

And that momentum? Starts with BDNF.

goBHB Dosing: How Much You Need—And Why Even a Little Might Do A Lot

goBHB Dosing: How Much You Need—And Why Even a Little Might Do A Lot

By: Marc Lobliner, IFBB Pro

We’ve said it before and we’ll say it again: goBHB® is a game-changer. As one of the most efficient and research-backed ketone fuels available, it supports performance, cognition, energy, appetite control, and more. But one question comes up over and over again:

How much goBHB do I really need to feel the effects?

Traditionally, doses of 6 to 12 grams per serving have been used in supplements and clinical studies. But here’s where things get interesting: we’ve seen mounting anecdotal evidence that doses as low as 250 to 500 milligrams can deliver noticeable benefits for certain users and specific goals.

That doesn’t mean higher doses are ineffective—in fact, quite the opposite. Higher doses may amplify endurance, blood ketone levels, recovery, and anti-inflammatory effects. But it’s becoming clear that even small amounts of goBHB may offer meaningful support, especially for mental energy, focus, and appetite regulation.

Let’s break it down.


What is goBHB?

goBHB® is a patented, exogenously produced form of beta-hydroxybutyrate (BHB)—the primary ketone your body produces during fasting or carbohydrate restriction. At Ketone Labs, we offer a full-spectrum BHB that includes both D- and L-isomers, reflecting the diversity of how BHB is utilized in human metabolism.

BHB is not just a fuel—it’s also a signaling molecule that interacts with multiple systems in the body, including the brain, muscles, and immune pathways. Whether you’re on a ketogenic diet or not, supplementing with goBHB delivers rapid, clean-burning energy without the jitters, crashes, or digestive stress of stimulants.


Traditional Dosing: 6–12 Grams

This is the clinically studied range you’ll find in most high-performance endurance, cognitive, and weight-management products.

Why this range?

  • It’s the amount needed to raise blood ketone levels to ~0.5–1.0 mmol/L—levels associated with nutritional ketosis

  • Research in athletes shows improvements in time-to-exhaustion, mental focus, and reduced appetite

  • Clinical trials often standardize around this range to ensure consistent, measurable changes in biomarkers

For anyone looking to use goBHB for serious training, recovery, appetite control, or even metabolic health, these higher doses are well-validated.


But What About Lower Doses?

Here’s where things get fascinating.

Through anecdotal reports, field testing, and early-stage data, we’ve observed that many individuals experience benefits at doses as low as 250–500mg. This includes:

  • Improved mental clarity and reduced brain fog

  • A subtle but noticeable boost in energy and focus

  • Blunted appetite and cravings between meals

  • Enhanced calm and resilience during stressful moments

These micro-effects seem to be especially noticeable when goBHB is taken in a dry format (like a chewable or powder), or on an empty stomach. Some users report feeling a difference within minutes—long before blood ketone levels would even spike.


The Potential Sublingual Effect

One theory gaining traction is that goBHB may partially absorb through the sublingual (under-the-tongue) route, especially when taken in dry form.

Why this matters:

  • BHB is a small, water-soluble molecule, much like glucose analogs and amino acids

  • Sublingual absorption bypasses digestion and the liver, potentially allowing faster entry into the bloodstream

  • Users taking 250–500mg dry, under the tongue or in chewable form, often report rapid onset effects

At Ketone Labs, we’re actively exploring this hypothesis in controlled environments. While more data is needed, the early signals are promising—and could change the way we think about delivery methods in ketone supplementation.


Why Less Might Work

Here’s the key takeaway: you don’t always need to chase a big number on your ketone meter to feel better, think clearer, or perform stronger.

Small amounts of goBHB may:

  • Support brain energy metabolism and mood regulation

  • Trigger cellular signaling pathways involved in inflammation control, mitochondrial efficiency, and gene expression

  • Act as a metabolic primer, giving your body just enough of a clean-burning fuel to elevate performance



Where the Research is Going

At Ketone Labs, we’re not just making bold claims—we’re backing them with science. Here’s what we’re currently exploring:

  • The minimal effective dose of goBHB for various benefits (focus, appetite, training)

  • How lower daily doses may support brain function, inflammation markers, and long-term metabolic health

  • Whether mixed-isomer forms (L+D) offer broader benefit profiles than isolated isomers

We’re committed to transparency, innovation, and giving consumers real, research-backed dosing guidance as the data emerges.



Final Thoughts

goBHB isn’t just a keto supplement—it’s a human performance tool. Whether you’re training hard, thinking deeply, or just trying to stay sharp, it’s one of the cleanest, most versatile fuels you can put in your body.

While 6 to 12 grams per day remains a gold standard for many goals, don’t overlook the power of a precision approach. With emerging evidence that even 250–500mg may provide benefits, we’re entering a new era of micro-targeted metabolic support.

At Ketone Labs, we’re proud to lead the way with full-spectrum goBHB and cutting-edge research that puts real results—and real science—in your hands.

Stay tuned. We’re just getting started.


References

  1. Veech, R.L. (2004). The therapeutic implications of ketone bodies. Prostaglandins Leukot Essent Fatty Acids, 70(3), 309–319.

  2. Cox, P.J., et al. (2016). Nutritional Ketosis Alters Fuel Preference and Endurance Performance in Athletes. Cell Metabolism, 24(2), 256–268.

  3. Stubbs, B.J., et al. (2017). Exogenous ketone supplements reduce appetite and hunger in overweight humans. Appetite, 117, 23–33.

  4. Shojaei, A.H. (1998). Buccal mucosa as a route for systemic drug delivery: a review. J Pharm Pharm Sci, 1(1), 15–30.

  5. Youm, Y.-H., et al. (2015). The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease. Nat Med, 21(3), 263–269.

  6. Shimazu, T., et al. (2013). Suppression of oxidative stress by β-hydroxybutyrate, an endogenous HDAC inhibitor. Science, 339(6116), 211–214.

Why Every Endurance Supplement Should Include goBHB

Why Every Endurance Supplement Should Include goBHB

By: Marc Lobliner, IFBB Pro

I don’t care if you’re a triathlete, marathoner, cyclist, or just a weekend warrior putting in the miles—if your endurance formula doesn’t include goBHB, it’s incomplete. Period. The science is there, the performance is real, and the benefits go far beyond energy.

We’re not just talking about “keto” here. We’re talking about one of the most efficient fuels your body can run on—beta-hydroxybutyrate (goBHB)—and why it should be in every single product marketed for endurance.


1. goBHB Is a Clean, Efficient Fuel Source

goBHB is a ketone body, a natural energy substrate your body produces during fasting, carbohydrate restriction, or extended exercise. But when you take it exogenously (as a supplement), your body gets all the energy benefits of ketosis—without the diet.

Let’s get technical for a second.

When you consume goBHB:

  • It skips glycolysis and goes straight into the mitochondria for ATP production.

  • It produces more ATP per unit of oxygen than glucose or fat [1].

  • That means you get more energy output with less oxygen demand, which is exactly what you need during endurance performance.

In high-output situations like marathons, ultra events, or long training sessions, your body starts to deplete glycogen. Instead of hitting the wall, goBHB provides an immediate alternate fuel source that spares glycogen and prolongs performance [2].


2. goBHB Delays Fatigue and Preserves Muscle

Ever bonk on a run or cramp up on mile 20? That’s your body crying out for fuel and balance. BHB helps solve that.

In a study published in Cell Metabolism, elite cyclists who supplemented with ketones experienced 28% greater endurance performance compared to those who didn’t [3]. That’s not a small edge—that’s a podium-level advantage.

And there’s more:

  • BHB has anti-catabolic properties, meaning it reduces muscle breakdown during prolonged training [4].

  • It blunts the rise in cortisol and other stress hormones that normally go through the roof in ultra-endurance efforts.

  • It also enhances recovery by reducing inflammation and oxidative stress post-exercise [5].

Translation: You can go longer, recover faster, and stay leaner.


3. Electrolyte Co-Delivery = Better Hydration + Cramp Prevention

goBHB doesn’t come alone. It’s typically bonded to essential electrolytes like sodium, calcium, and magnesium—making it a dual-action endurance tool.

Think about it:

  • You lose sodium, potassium, and magnesium through sweat.

  • You need to replenish those to avoid cramps, fatigue, and brain fog.

  • goBHB-based salts do exactly that, while also delivering clean fuel.

Most endurance supplements throw in electrolytes and call it a day. But with goBHB, you’re combining electrolyte support + metabolic enhancement in one.

This makes it an obvious choice for hot-weather races, long-distance events, or even fasted cardio.


4. Cognitive Focus and Mental Clarity Under Fatigue

You’re not just racing your body—you’re racing your mind.

When glucose runs low, brain fog and poor decision-making set in. BHB crosses the blood-brain barrier and acts as an alternative fuel for your brain, giving you heightened clarity and focus when others are crashing mentally [6].

In high-stakes endurance events, one bad decision can cost you the race. goBHB helps keep your brain firing when it counts most.


5. It Works WITH Carbs — Not Against Them

Let’s kill the myth: you don’t need to be on a keto diet to benefit from ketones.

goBHB can be taken with carbs. In fact, studies show stacking ketones with carbs improves endurance performance even further [7]. Carbs refill glycogen. Ketones preserve it and offer a parallel energy stream. It’s the best of both worlds.

So endurance supplements shouldn’t ditch carbs—they should add goBHB to enhance them.


The Bottom Line

If you’re formulating an endurance product and you’re leaving out goBHB, you’re doing it wrong. Athletes want more than just sugar, sodium, and caffeine. They want:

  • Clean energy

  • Muscle protection

  • Electrolyte balance

  • Mental focus

  • Faster recovery

And goBHB delivers on all of it.

It’s time to evolve endurance nutrition. And that starts with adding goBHB to every endurance stack out there.


Train longer. Recover faster. Perform better.


📚 References:

  1. Veech, R.L. (2004). “The therapeutic implications of ketone bodies.” Prostaglandins Leukot Essent Fatty Acids, 70(3), 309–319.

  2. Pinckaers, P.J., et al. (2017). “Exogenous ketone supplementation and endurance exercise performance.” Sports Medicine, 47(3), 513–523.

  3. Cox, P.J., et al. (2016). “Nutritional Ketosis Alters Fuel Preference and Endurance Performance in Athletes.” Cell Metabolism, 24(2), 256–268.

  4. D’Agostino, D.P., et al. (2013). “Ketone bodies and protection against muscle wasting.” Nutrition & Metabolism, 10:29.

  5. Stubbs, B.J., et al. (2017). “On the Metabolism of Exogenous Ketones in Humans.” Frontiers in Physiology, 8, 848.

  6. Newman, J.C., et al. (2014). “Ketone Bodies Improve Cognition and Protect the Brain.” Neurobiology of Aging, 35(6), 1316–1323.

  7. Evans, M., et al. (2018). “Exogenous ketone supplementation improves time trial performance in elite cyclists.” Nutrition, 57, 1–7.