In this episode, Bonnie is joined by Mollee Rucker, founder of Keto Brainz Nootropics, and they discuss the transformative power of ketones and nootropics. Mollee shares her personal health journey, the science behind her unique product, and the entrepreneurial challenges of creating a high-quality brain-enhancing supplement. Discover how Keto Brainz can elevate your focus, clarity, and overall well-being, regardless of your diet.
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In this episode, Bonnie is joined by Mike Roberto and Ben Kane, owners of PricePlow, and they discuss their journey from a price comparison site to becoming influential insiders in sports nutrition. They dive into the most controversial current events in the supplement industry. They tackle the looming threats of new regulations, including mandatory product listings and age restrictions on supplements. The discussion exposes the industry’s struggles with legislative battles, the influence of Big Pharma, and the fight to protect essential ingredients like creatine. Learn about their passion for science-driven content, the importance of credible information, and how they navigate the industry’s challenges while staying true to their mission of education and transparency.
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Our patented BHB offers significant and unique support both during and after GLP-1 treatment through mitigating potential side effects like fatigue, nausea, vomiting, GI issue, increased heart rate, and most significantly preserves muscle mass. BHB also offers critical ongoing support after stopping GLP-1 treatments, in helping individuals maintain their weight and body composition goals.
This patented product would work synergistically with GLP-1 during and after use.
During GLP-1 use:
Post-treatment of GLP-1 use:
This multifaceted formulation makes it a powerful, needed companion to GLP-1 treatments.
Combines the fast-acting energy delivery of glucose with the sustained energy release of exogenous BHB (Beta-Hydroxybutyrate) ketones. The formulation utilizes moderate GL indexed carbohydrates for moderate blood glucose uptake and sustained glycogen replenishment and BHB to provide long lasting top tier ATP energy. The combined effect produces a dual fuel for both high-intensity fast twitch activity and extended range performance, with mental focus, fast recovery and reduced inflammation.
Target Audiences:
Today, there isn’t an integrated approach to performance workout nutrition. Almost all performance products focus on isolated moments of a workout, leaving you with energy spikes and crashes, incomplete recovery, and a constant struggle to reach your full potential.
The truth is your body needs a continuous flow of optimized fuel and nutrients to power through each stage of your workout – and beyond.
The Dual Fuel Performance Stack is a revolutionary 3-phase system that works in harmony with your body’s natural workout rhythms, delivering the precise combination of energy (BHB + Glucose) and other key ingredients your muscles and mind crave pre, during and post workout.
Dual Fuel. It’s time to experience a new level of performance, where your body and brain are in perfect sync, pushing your limits further than you ever thought possible.
The Dual Fuel Performance Stack isn’t just another group of supplements – it’s a complete reimagining of how to fuel your workouts. It’s a 3-phase system leveraging BHB (Beta- Hydroxybutyrate) and glucose, for the first time ever, to maximize performance and recovery throughout your training:
The Dual Fuel Performance Stack isn’t just another set of supplements; it’s a paradigm shift in how you fuel your workouts and unleash your full potential. By seamlessly integrating BHB and Glucose with other key nutrients, this revolutionary 3-phase system empowers you to ignite your energy, sustain your power, and accelerate your recovery like never before.
This provides the experience of unparalleled focus, endurance, and strength as you shatter plateaus and redefine your limits. The Dual Fuel Performance Stack is the future of performance in unlocking a level of physical and mental dominance never thought possible.
Obesity and type 2 diabetes have reached epidemic proportions, posing a significant health burden globally.
WHY IS LOSING WEIGHT SO CRITICAL TO ONE’S HEALTH?
WHY IS LOSING WEIGHT SO IMPORTANT TO THOSE WITH TYPE 2 DIABETES?
goBHBsupplementation is powerful in promoting weight loss and supporting Type 2 diabetes on any diet. The benefits include:
Obesity and type 2 diabetes have reached epidemic proportions, posing a significant health burden globally. As the prevalence continues to rise, there is a pressing need for effective strategies to manage these conditions. One promising approach involves the use of Beta-Hydroxybutyrate (BHB), a naturally occurring molecule produced by the body during periods of low glucose availability. This paper aims to explore the potential benefits of BHB in weight loss and the management of type 2 diabetes.
Obesity and overweightness have grown at alarming rates globally over the past few decades. The World Health Organization (WHO) has provided some key statistics:
A study published in The Lancet in 2016 analyzed data from nearly 4 million individuals worldwide, finding that for those overweight, every 5 units of BMI above 25 kg/m² was associated with about a 30% higher overall mortality rate.
There is no doubt that weight loss improves general health and especially for those suffering from type 2 diabetes.
Weight loss doesn’t happen unless you are successful at creating a calorie deficit. But creating a calorie deficit puts strain on the body to find fuel to keep it running outside of the fuel you consume. There are two choices, use fat mass for fuel or use muscle mass for fuel, both will cause weight loss, but only diets that preserve muscle and burn fat will be successful in the long term and reduce the effects of recidivism, the regaining of weight after the conclusion of a calorie restricted diet.
Science has proven a ketogenic or low carb diet outperforms a high carbohydrate diet in loosing fat mass versus muscle mass. This is because when the body does not have glucose to burn, nor the ability to convert muscle into glucose via a process called gluconeogenesis, it enters a state of ketosis when the body mobilizes its fat stores to provide triglycerides to the liver that converts the triglycerides into a high energy molecule called a ketone that can then fuel the body. It’s during this type of calorie restriction that the body loses fat, not muscle.
a common struggle for many people on calorie-restricted diets. Moreover, old habits can be hard to break, and new ones can be hard to form.
These challenges are both physiological and psychological and both challenges must be met to make any weight loss diet successful.
One proven strategy is the supplementation of Beta- Hydroxybutyrate (BHB), a ketone body naturally produced during periods of low carbohydrate and calorie intake that essentially help the body mimic ketosis, the fat burning state, regardless of the calories restrictive diet selected.
BHB supplements are exogenous sources of the ketone body BHB. They can mimic the physiological state of ketosis, where the body burns fat for fuel instead of glucose. While naturally occurring during fasting or a ketogenic diet, BHB supplements can significantly elevate ketone body levels in the body regardless of dietary intake, potentially offering unique metabolic and psychological advantages.
BHB supplementation aids fat loss by promoting a metabolic shift from glucose to fat utilization, enhancing fat breakdown. It attacks the physiological diet challenges through appetite suppression by influencing hunger-related hormones, significant increase in energy levels, especially in the brain, spares muscle and lowers glucose and insulin levels.
Studies show a correlation between elevated BHB levels from supplements and weight loss in:
Psychologically BHB supplementation has been shown to improve mood and relieve normal stress and anxiety. These psychological benefits help people make better food choices, reduce emotional and social eating issues, and maintain their discipline in sustaining their diet.
Here is the bottom line of why BHB Supplementation is so powerful in promoting weight loss and supporting Type 2 diabetes on any diet:
By inducing a state of ketosis, even without a strictly low carb or ketogenic diet, BHB can help the body utilize stored fat for energy, promoting fat loss over muscle loss. This can be particularly beneficial for individuals on a calorie-restrictive diet, aiding in the preservation of lean muscle mass while promoting fat reduction. Moreover, the potential of BHB to reduce feelings of hunger and cravings can help individuals adhere to their calorie-restrictive diets more effectively, addressing one of the significant challenges of such diet protocols.
Beyond weight loss, BHB’s role in improving cognitive function, reducing inflammation, and potentially improving insulin sensitivity may offer additional health benefits, contributing to an overall improvement in metabolic health.
In conclusion, the use of Beta-Hydroxybutyrate (BHB) supplementation can serve as the perfect strategy to capture the benefits of a calorie-restrictive diet. Its potential to stimulate the body’s natural fat-burning processes, curb hunger pangs, and offer a high-powered energy source can enhance the weight loss journey, by reducing fat, sparing muscle, and improving mood. goBHB makes any calorie restrictive diet more efficient and sustainable.
REFERENCES
BHB unleashes an energy surge that ATP disodium simply cannot match.
This brief analysis delves into the multifaceted superiority of BHB, exposes the limitations of ATP disodium while highlighting BHB’s efficiency and advantages as the supreme fuel source.
Why BHB Is Superior to Peak ATP
Direct vs Indirect:
Absorption:
Metabolic Efficiency:
Cellular Signaling:
BHB is a superior fuel source in terms of net ATP it provides to cells. The effectiveness of BHB in boosting energy availability indirectly overshadows potential direct ATP supplementation studies, especially given absorption concerns.
Normal stress and anxiety are common experiences that can have very negative effects on physical and mental health.
There are many triggers that can lead to disproportionate stress and anxiety, and they can vary greatly depending on the individual. Some common triggers include:
HOW DOES goBHB HELP REDUCE NORMAL STRESS AND ANXIETY?
Normal stress and anxiety are common experiences that can have negative effects on physical and mental health. Understanding the size of the problem, the populations most affected, the causes, and ways to reduce stress and anxiety is important for reducing potential debilitation from stress and anxiety.
According to the American Psychological Association (APA), stress levels in the United States have been steadily increasing in recent years. In the APA’s 2021 Stress in America survey, 84% of adults reported experiencing at least one emotion associated with prolonged stress in the past two weeks, such as anxiety, sadness, or anger. Additionally, 54% of adults reported that their stress levels had increased in the past year.
Stress and anxiety can affect people of all ages, races, and ethnicities. However, some populations may be more affected than others. Women are more likely than men to experience anxiety disorders, while men are more likely to experience stress- related disorders such as post-traumatic stress disorder (PTSD). Some racial and ethnic groups may be more likely to experience anxiety disorders, although the reasons for this are complex and not fully understood. Certain professions, such as those that involve high levels of stress or trauma, may also be more affected by stress and anxiety.
Normal stress and anxiety can be defined as our natural responses to challenging or threatening situations and can help us to cope with difficult circumstances. Stress and anxiety are considered normal when they are proportional to the situation that is causing them, and they do not significantly interfere with daily activities or overall quality of life.
But there are stressors or triggers that distort what might be considered proportional to a situation and in these cases normal stress and anxiety becomes excessive and can have negative effects on physical and mental health and lessen one’s ability to act towards stress and anxiety appropriately.
There are many triggers that can lead to disproportionate stress and anxiety, and they can vary greatly depending on the individual. However, some common triggers include:
BHB reduces inflammation: Chronic inflammation can contribute to stress and anxiety. BHB has been shown to have anti-inflammatory effects, which may help to reduce inflammation and the associated stress and anxiety.
One possible mechanism by which BHB works to reduce inflammation is through the activation of the NLRP3 inflammasome. The NLRP3 inflammasome is a protein complex that plays a key role in the inflammatory response, and its activation can lead to the production of pro-inflammatory cytokines. In a study done at Yale University, BHB has been shown to inhibit the activation of the NLRP3 inflammasome, which can help to reduce inflammation and the associated stress and anxiety.
Additionally, BHB has been shown to have antioxidant effects, which can help to reduce oxidative stress (ROS) and inflammation. Oxidative stress occurs when there is an imbalance between the production of ROS and the body’s antioxidant defenses. ROS can damage cells and contribute to the development of stress and anxiety. BHB has been shown to increase the production of antioxidant enzymes, such as superoxide dismutase (SOD), which can help to reduce oxidative stress and inflammation.
BHB increases GABA levels: GABA is a neurotransmitter that helps to regulate mood and reduce anxiety. BHB has been shown to increase GABA levels in the brain, which may help to reduce anxiety and promote feelings of calmness. GABA is an inhibitory neurotransmitter that plays a key role in regulating anxiety and promoting feelings of calmness. Low levels of GABA have been linked to the development of anxiety disorders. BHB has been shown to increase GABA levels in the brain, which can help to reduce anxiety and promote relaxation.
One possible mechanism by which BHB works to increase GABA levels is through the inhibition of histone deacetylases (HDACs). HDACs are enzymes that play a key role in regulating gene expression, and they have been shown to decrease the expression of genes that encode GABAergic neurotransmitters. BHB has been shown to inhibit HDACs, which can increase the expression of GABAergic genes and lead to an increase in GABA levels in the brain.
Another possible mechanism by which BHB works to increase GABA levels is through the activation of G-protein coupled receptors. BHB has been shown to activate the G-protein coupled receptor GPR109A, which is expressed on the surface of certain cells in the brain. Activation of GPR109A can lead to an increase in the production of GABA and the release of GABA from neurons.
BHB improves brain function: BHB has been shown to increase brain-derived neurotrophic factor (BDNF), a protein that is important for brain function and cognitive health. Improving brain function may help to reduce stress and anxiety by improving the body’s ability to cope with stressors. BHB is the body’s preferred energy source for the brain that can provide more ATP energy than glucose. By providing a higher level and purer source of energy, BHB has been shown to improve cognitive function and memory in animal studies. This may be due to its ability to increase energy supply to the brain and improve neuroprotection and antioxidant activity. BHB can help to improve overall brain function and performance. This allows the brain to more easily and quickly deal with issues and situations such that they do not become disproportionate to the issue or situation improving coping and solution alternatives.
BHB increases resilience to stress: BHB has been shown to increase the body’s ability to cope with stress by activating stress response pathways. This increased resilience to stress may help to reduce feelings of anxiety and promote a sense of well-being. BHB has been shown to increase resilience and improve the body’s ability to cope with stress. This can be particularly beneficial for individuals experiencing stress and anxiety, as it can help to reduce the negative effects of stress on brain function and cognitive performance.
BHB improves sleep quality: Poor sleep quality can contribute to stress and anxiety. BHB has been shown to improve sleep quality by increasing levels of the hormone melatonin, which is important for regulating sleep-wake cycles. BHB has been shown to increase the production of melatonin, a hormone that helps to regulate the sleep-wake cycle. By increasing melatonin production, BHB can help to promote a more regular sleep-wake cycle and improve sleep quality.
BHB is a high energy fuel source for the brain that can provide more energy than glucose, which is particularly beneficial during sleep. BHB has been shown to reduce sleep disturbances, allowing for deeper sleep, with reduced wakefulness and restlessness. This may be due to its ability to promote relaxation and improved energy metabolism.
BHB (beta-hydroxybutyrate) has several powerful benefits for reducing normal stress and anxiety. While the exact mechanisms by which BHB works to reduce stress and anxiety are not fully understood, there is significant evidence to suggest that it may involve several different mechanisms, including anti-inflammatory effects, increased GABA levels, and improved brain function.
Overall, the available study evidence suggests that BHB may be one of most significant supplements in addressing the issue of normal stress and anxiety. It may be particularly beneficial for individuals who are looking for natural and non-pharmacological way to manage stress and anxiety daily.
goBHB is and will be one of the true keys to achieving metabolic health, improved wellness, the slowing of aging, and improving longevity. Simply put, goBHB is the master energy molecule capable of:
BHB has attracted significant attention due to its potential health benefits beyond its role in energy metabolism. Researchers have been exploring the physiological mechanisms underlying the positive effects of BHB on wellness, metabolic health, and longevity.
According to the Global Burden of Disease Study conducted in 2017, it was estimated that around 95% of the global population had at least one health problem or illness, with the remaining 5% considered completely healthy. This study encompassed a wide range of diseases, including both communicable and non- communicable diseases, injuries, and other health conditions.
Deaths caused by chronic illnesses and related diseases are on the increase worldwide. The percentage of deaths from natural causes versus deaths from disease related causes varies depending on the country and the age group. In the United States, for example, about 80% of deaths in people over the age of 65 are from disease related causes, while about 20% are from natural causes.
Natural causes include things like old age, accidents, and injuries. Disease related causes include things like cancer, heart disease and stroke.
The percentage of deaths from natural causes is decreasing over time as people live longer and healthier lives. The percentage of deaths from disease related causes is increasing over time as people are living longer and are more likely to develop chronic diseases.
Here are some of the leading causes of death in the United States:
As to aging and longevity, life expectancy in the USA has dropped over the past five years. In 2017, life expectancy at birth was 78.6 years. By 2022, it had dropped to 76.1 years. This is a decline of
2.5 years. Coupled with this, the Numbeo Quality of Life Index has dropped over the past five years. In 2017, the average score for all countries was 61.1. By 2022, the average score had dropped to
59.5. This is a decline of 2.8%.
By focusing on obesity in the context of metabolic health, wellness and aging, we can see that obesity leads to major risk factors for many chronic diseases including heart disease, stroke, type 2 diabetes and some types of cancer. A study published in the journal JAMA found that obesity can shorten a person’s life expectancy by an average of 3 to 10 years. The study looked at data from over 100,000 people and found that those who were obese were more likely to die from heart disease, stroke, type 2 diabetes, and some types of cancer.
Metabolic health refers to the overall state of an individual’s metabolic functioning, particularly in relation to the processing, utilization, and regulation of energy and nutrients within the body. It involves the proper functioning of metabolic pathways, hormones, enzymes, and organs involved in metabolism such as the liver, pancreas, adipose tissue, and muscles.
Metabolic health is characterized by the body’s ability to efficiently convert food into energy, maintain stable blood glucose levels, regulate lipid metabolism, and effectively utilize and store nutrients. It is associated with factors such as insulin sensitivity, glucose control, lipid profiles, blood pressure, and body composition.
A person with good metabolic health typically exhibits balanced energy metabolism, with efficient utilization of glucose and fatty acids for energy production. They have stable blood glucose levels, low levels of circulating insulin, and a healthy lipid profile, including optimal levels of triglycerides, cholesterol, and lipoproteins. Additionally, individuals with good metabolic health tend to have a healthy body weight, favorable body composition (appropriate ratio of lean mass to fat mass), and normal blood pressure.
On the other hand, poor metabolic health is often characterized by conditions such as insulin resistance, impaired glucose tolerance, dyslipidemia (abnormal lipid profile), obesity, and elevated blood pressure. These conditions increase the risk of developing metabolic syndrome, type 2 diabetes, cardiovascular diseases, and other metabolic disorders.
Overall, metabolic health reflects the body’s ability to carry out metabolic processes effectively and harmoniously, promoting optimal energy utilization, nutrient metabolism, and overall well- being.
Several studies have indicated that good metabolic health is relatively rare in many populations, particularly in developed countries where sedentary lifestyles, unhealthy diets, and obesity rates are higher. For example, a study published in the journal Metabolic Syndrome and Related Disorders in 2014 found that only 12.2% of American adults had optimal metabolic health based on criteria such as blood pressure, glucose control, lipid profiles, and body composition.
goBHB supplementation is a safe and effective way to improve metabolic health. It has been proven to:
Here are some studies that support the benefits of BHB for metabolic health:
Wellness can be defined as a state of overall well-being encompassing various dimensions of health, including physical, mental, emotional, social, and spiritual well-being. It goes beyond the absence of illness and incorporates aspects such as optimal physical fitness, mental clarity, emotional balance, positive social relationships, and a sense of purpose and fulfillment.
Wellness involves actively pursuing a healthy and balanced lifestyle, making conscious choices that promote health, and striving for a harmonious integration of mind, body, and spirit. It is a dynamic process that requires continuous effort and self- care to achieve and maintain an optimal state of well-being. Wellness is about optimizing health, energy and vitality rather than managing disease.
Wellness is important because it’s a state of existence that can help you live a longer, healthier and happier life. When you are well, you have more energy, you are better able to cope with stress, and you are more likely to make healthy choices. Wellness can also help you to improve your relationships, your work performance, and most of all your overall quality of life. If you are not healthy it detracts from almost all aspects of your life.
In addition to supplementation with exogenous ketones, there are things that can be done to improve your wellness. Some of the most important things from a health perspective include:
goBHB can help get the body into a ketogenic state. Ketosis is a metabolic state in which the body utilizes ketones for energy. BHB has been shown to have several benefits for health and wellness, including:
BHB is a better metabolic fuel. Its more powerful, cleaner, and does not require an active transport to move it into mitochondria. BHB impacts wellness and if taken regularly can improve many different bio-markers of health.
Aging is a metabolic condition associated with the loss of mitochondria and mitochondrial function. As cells age, mitochondria can become damaged by oxidative stress and other factors associated with aging. This reduction in the number and efficiency of cell mitochondria leads to a diminished capacity for producing ATP.
ATP is the basic currency of energy used by the muscles, brain, organs, and other biological functions. As ATP production slows, the body reacts by shutting down biological functions that are less essential—such as cell proliferation, including the formation of new skin cells, heart cells, brain cells—to ensure that there is enough ATP to carry out the metabolic functions essential for maintaining life (such as those pertaining to the brain, heart, and other vital organs). The body acts on these choices by using epigenetic switching to silence the genes associated with less vital bodily functions. The goal is to keep all the switches turned on to all the vital bodily functions.
Another key factor related to aging is oxidative stress. It is considered one of the hallmarks to aging and thought to actively contribute to the development of chronic diseases, including neurodegeneration. Normal physiological reactions in the body, as well as exogenous sources, produce reactive oxygen species (ROS). Over time, accumulation of ROS-related damage leads to age-associated tissue and organ function losses. The accumulation of ROS-related damage results from increased production of ROS and/or decreased antioxidant defenses against the ROS. Excessive ROS causes aging by damaging organs, tissue, and DNA directly through oxidizing bases, causing strand breaks. Indirectly ROS can impact DNA damage through Ionizing radiation, UVA radiation, and chemical agents. It has been suggested that the age-associated decline in blood levels of certain antioxidants may be a risk factor for neurodegeneration in the elderly.
Whether you are talking metabolic health, wellness or aging, preventing cellular senescence, a state of irreversible cell cycle arrest in which a cell loses its ability to divide and proliferate, is key to vital living. Senescence can be triggered by various factors, including DNA damage, telomere shortening, oxidative stress, oncogene activation, and certain cellular stressors. All though senescent cells remain metabolically active they undergo significant changes in their gene expression, morphology, and function. As humans age, metabolic health and wellness become the challenge and reducing the number of senescent cells becomes the objective. As senescent cells increase they can impair tissue function and contribute to chronic inflammation. Senescent cells secrete various pro-inflammatory factors, growth factors, and matrix-degrading enzymes, collectively known as the senescence-associated secretory phenotype (SASP). The SASP can promote tissue dysfunction, chronic inflammation, and the development of age-related pathologies.
The control and removal of senescent cells is critical for overall metabolic health and wellness. Senescent cells can release harmful factors that can damage surrounding cells and tissues. They can also interfere with the normal function of organs and tissues. BHB helps to control and remove senescent cells in a number of ways.
First, BHB can induce the death of senescent cells through a process called apoptosis. Apoptosis is a natural process of cell death that is important for maintaining the health of the body. BHB can induce apoptosis in senescent cells by activating a protein called p53. p53 is a tumor suppressor protein that plays a role in regulating cell growth and death. In a study published in the journal Nature Medicine, researchers found that BHB was able to induce apoptosis in senescent cells. The researchers also found that BHB was able to suppress the production of inflammatory factors by senescent cells. Dr David Sinclair, author of ‘Lifespan’ has shown how a low sugar diet maintains cell health and prevents cell senescence; this contributes to fewer biomarkers of disease (and aging) and longer lifespans.
Second, BHB can suppress the production of inflammatory factors by senescent cells. Inflammatory factors can damage surrounding cells and tissues and contribute to the development of diseases. BHB can suppress the production of inflammatory factors by senescent cells by activating a protein called AMPK. AMPK is a metabolic sensor that plays a role in regulating inflammation.
Third, BHB can increase the production of antioxidants by the body. Antioxidants can help to protect cells from damage by free radicals. Free radicals are unstable molecules that can damage cells and tissues. BHB can increase the production of antioxidants by the body by activating a protein called Nrf2. Nrf2 is a transcription factor that regulates the expression of genes involved in antioxidant defense. In a study published in the journal Aging, researchers found that BHB was able to increase the production of antioxidants by the body. The researchers also found that BHB was able to protect cells from damage by free radicals.
Fourth, BHB can help elevate the effects of fasting, exercise and calorie restriction in causing autophagy.
Longevity is the length of time a person or organism lives. Although longevity and aging are associated with each other, aging is a process and longevity is an outcome. It is somewhat intuitive to think that the prevention of aging automatically increases longevity, but that is not necessarily true. Someone can slowly age and then suddenly succumb to a sudden chronic disease, or lose their cognitive functionality as in the case in dementia and Alzheimer’s disease.
Longevity is such a pervasive goal in everyone’s life, in our public health policies and in popular social media that billions of dollars are spent trying to achieve this elusive goal. There are perhaps as many reasons for wanting to live longer as there are individuals.
However, coupled to living longer is the quality of life issue. In many different surveys most people only want to live longer lives if it will translate to quality healthy living. So even as longevity is a very valued public health objective, at the individual level longer lives are a goal only if people can remain healthy.
Looking at aging and longevity in a holistic view, it is arguable that healthy aging provides the means for enjoyable longevity. This means a long disease ridden life has been judged to have less value than a shorter healthy and active life.
Fundamentally, aging contains both a metabolic and genetic component. Aging is recognized as a complex process that involves both metabolic and genetic factors, including changes in cellular processes, DNA damage, and the accumulation of cellular waste can lead to a decline in physiological function and an increased risk of age-related diseases. While aging is presently thought to be a natural and unavoidable process, certain dietary lifestyle choices along with proper supplementation strategies can be utilized to not only (1) slow down or even reverse the aging process, but (2) promote overall health that leads to quality longevity.
Two major factors contributing to aging is the decline in mitochondrial function and mitochondrial proliferation.
The metabolism of BHB is associated with several beneficial effects including anticonvulsant effects, enhanced metabolism by the brain, neuroprotection, muscle sparing properties, and improved cognitive and physical performance. Science-based improvements in efficiency of cellular metabolism, managed through BHB supplementation, can have beneficial impacts on physical and cognitive health, psychological health, and a long-term impact on health with respect to the common avoidable diseases such as obesity, cardiovascular disease, neurodegenerative diseases, diabetes, and cancer. Many of these are associated with aging and loss of a quality of life status.
BHB has been found to be a vital metabolic and signaling mediator with different biological roles coming from the different enantiomers of beta hydroxybutyrate. BHB is known to have a repertoire of therapeutic benefits and provide options for mitigating diseases of the nervous system, with prospective roles in cancer, as well as having intriguing protective roles in heart and liver, opening therapeutic options in obesity-related and cardiovascular
disease. The signaling capability of ketones is continued to be explored in their ability to turn on and off different epigenetic and metabolic switches through ketone metabolism removing much of the classical dogma of ketones simply being an energy metabolite with limited function and application.
Recent studies now point to additional roles for BHB in cellular metabolism, metabolic homeostasis, and a wide range of signaling of physiological, epigenetic and pathological states. Apart from serving as the body’s preferred energy fuel for extrahepatic tissues like the brain, heart, or skeletal muscles, ketone bodies appear to play pivotal roles as signaling mediators, drivers of protein post-translational modification (PTM), and significant modulators of inflammation and oxidative stress. Moreover, research is now starting to point to BHB as having the ability to mediate epigenetics opening a whole new world of modern thinking about the role of ketone bodies and their metabolism in human function and health.
BHB is processed differently in the mitochondria than glucose. BHB gives mitochondria their unique characteristics in the production of ATP, reduces reaction oxygen species and reduces oxidative stress on a cellular level.
BHB has numerous positive metabolic impacts such as:
BHB will be one of the key ingredients to mastering aging and longevity in our lifetimes.
BHB is and will be one of the true keys to achieving metabolic health, improved wellness, the slowing of aging, and improving longevity. Simply put BHB is the master energy molecule capable of:
BHB has the potential to improve a variety of health conditions that promote wellness. BHB is a safe and natural compound that can be used by people of all ages and health conditions.
Intermittent fasting is America’s #1 followed lifestyle diet. Intermittent Fasting is an established eating plan that switches between fasting and eating on a regular schedule.
There are key reasons why people choose to practice intermittent fasting, including:
Challenges of Intermittent Fasting
Hormonal differences between men and women that could potentially impact the effectiveness of intermittent fasting. Strategies that women can do to optimize their fasting results:
Using goBHB to boost your Intermittent Fasting provides:
Intermittent fasting is America’s #1 followed lifestyle diet. Put simply, Intermittent Fasting is an established daily eating plan that switches between fasting and eating on a regular schedule. In 2020, 24% of USA adults, approximately 62,000,000 had tried intermittent fasting! Intermittent fasting is now the most popular diet, over taking the highly popular keto diet.
There are key reasons why people choose to practice intermittent fasting, including:
While intermittent fasting can offer great health benefits, it can also pose some tough challenges, including:
While intermittent fasting can offer great health benefits to both men and women, a significant complaint from intermittent fasting women is they do not see the same early weight loss results that is achieved by men. While this has been observable, It is also important to note that “success” with intermittent fasting can be measured in other ways than weight loss. Other potential benefits, such as improved metabolic health or increased longevity, are both benefits for men and women.
However, in recognition of the often described differences of intermittent fasting for women versus men, there are some key biological and hormonal differences between men and women that could potentially impact the effectiveness of intermittent fasting:
During an intermittent fast, the body begins to burn stored fat for energy, which leads to an increase in ketone production, especially BHB. Typically, after an overnight fast, the body will start producing ketones, including BHB, within a few hours. The levels of BHB in the blood will then gradually increase over time, peaking after 24-72 hours of fasting. While the levels of BHB after 16 hours of fasting can vary widely between individuals, studies have shown that typically, after 12-24 hours of fasting, BHB levels can range from 0.2 to 1.5 mmol/L.
The hallmark mechanisms of fasting are the increase of BHB and reduced caloric intake. Coupled together they form the basis for producing all the benefits derived during an intermittent fast. The greater the BHB, the greater the benefits.
And while your body makes a limited number of ketones during your fasting hours, they aren’t enough to always overcome the Challenges and deliver all the benefits mentioned above.
Using goBHB to boost your Intermittent Fasting provides:
While recognizing the biological and physiological differences between men and women, these differences can affect how each gender responds to intermittent fasting. In addition to adding energy and nutrition, there are several strategies that women can also utilize to optimize their experience and results:
goBHB is the ONLY energy rich macronutrient fuel that you can take that DOESN’T break your fast, that overcomes the Challenges of Intermittent Fasting while enhancing all the benefits your body gets from being in a fasting state.
In a dynamic, ever-growing world focused on improving cellular energy and metabolism, Beta-Hydroxybutyrate (BHB) stands out as the most exceptionally versatile and efficient cellular fuel source. BHB is an evolutionary and crucial molecule that surpasses any other cellular energy source in its ability to positively impact health, longevity, and performance, making BHB the gold standard for cellular energy.
Glucose, primarily derived from carbohydrates, was previously considered the body’s preferred fuel. Studies discover that glucose is a “dirty” fuel, meaning that as it is metabolized in the body and produces energy, it also produces harmful byproducts. Below are some health concerns that are the results of a glucose fed cellular energy state.