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Formulators Guide To Enantiomeric Ratios Of (D) And (L) By Category And Subcategory

The ratios of D/L arise from the specific physiological and biochemical needs addressed by each subcategory.

While the main category sets the overarching theme—such as energy optimization for goBHB® Active or cognitive enhancement for goBHB® Neuro—each subcategory within it focuses on a distinct aspect of performance or health that requires tailored support.

For example, within goBHB Active, performance-focused subcategories may prioritize D-BHB for immediate ATP production, while recovery-oriented subcategories may benefit from a slightly higher proportion of L-BHB to aid in inflammation management and oxidative stress reduction.

Similarly, in goBHB Neuro, cognition and focus might emphasize balanced ratios for sustained energy and neurotransmitter modulation, whereas sleep requires greater L-BHB for its role in mood stabilization and neuroprotection.

These variations ensure that each subcategory receives a ratio optimized for its unique demands. By addressing the nuanced requirements of each subcategory, the formulas achieve precision and flexibility within a unified framework.


goBHB® Active

goBHB Active reflects the need for an energy-dominant composition that also incorporates signaling support for recovery and stress adaptation. D-BHB is heavily involved in ATP production, which is critical for athletic performance, endurance, and pre-workout energy. It ensures the body has sufficient immediate energy for physical activities by directly supporting mitochondrial function.

However, L-BHB contributes to oxidative stress mitigation and muscle recovery, as demonstrated in our neurotransmitter study. The L-BHB component helps regulate glutamate and GABA balance, reducing excitotoxicity and stabilizing neural networks during and after intense physical exertion. This ratio provides a synergistic blend, ensuring sustained performance while minimizing oxidative damage.

SubcategoryD:L RatioSuggestions on Additive or Synergistic Ingredients to Add
Dual Fuel80/20D-Ribose, Cluster Dextrin, Glucose
Performance75/25Betaine Anhydrous, Creatine, Citrulline
Recovery70/30Tart Cherry Juice, Pine Bark Extract
Endurance80/20Pyrroloquinoline Quinone, Carbohydrates, Electrolytes
Pre-workout75/25Caffeine, L-Carnitine, Beta Alanine
Hydration80/20L-Alanyl-L-Glutamine, Sodium, Potassium, Magnesium, Calcium, Zinc

goBHB® Neuro

goBHB Neuro underscores the importance of energy production and signaling for cognitive function. D-BHB enhances dopamine and serotonin synthesis in the hippocampus, promoting focus, memory, and mental clarity. Meanwhile, L-BHB plays a vital role in mood regulation and stress reduction through its influence on serotonin pathways and glutamate-GABA balance.

SubcategoryD:L RatioSuggestions on Additive or Synergistic Ingredients to Add
Flow30/70B-Vitamins, Paraxanthine
Cognition and Focus45/55Citicoline, alpha-Glycerophosphocholine
Memory, Cog Decline35/65Citicoline, Huperzine A
Sleep40/60Glycine, GABA, Lactium
Vision50/50Lutein, Zeaxanthin, Cyanidin-3-Glucoside
Stress/Anxiety40/60Theanine, Ashwagandha

goBHB® Renew

goBHB Renew prioritizes energy production while incorporating a robust signaling component to support cellular health and longevity.

SubcategoryD:L RatioSuggestions on Additive or Synergistic Ingredients to Add
ATP85/15Glucose, D-Ribose, Adenosine Triphosphate Sodium, Creatine, Carnitine
Inflammation70/30Curcumin, Boswellia, White Willow Bark
Mitochondria Support70/30Pyrroloquinoline quinone, Carnitine, Urolithin A
Heart Health70/30Coenzyme Q10, Garlic
Longevity70/30Fisetin
Metabolism75/25Beta-Aminoisobutyric Acid, Dihydroberberine, Bitter Melon Extract
Cellular Function75/25See above

goBHB® Lean

goBHB Lean reflects the need for a slightly higher energy emphasis to support metabolic processes like appetite suppression and weight loss while leveraging L-BHB’s signaling properties for metabolic and neurocognitive balance.

SubcategoryD:L RatioSuggestions on Additive or Synergistic Ingredients to Add
Appetite Suppression60/40Konjac Fiber (Glucomannan), DNF-10 Peptides, Saffron Extract
Semaglutides50/50Pep2Dia (Milk Peptides), Lemon Bioflavonoids, Butyric Acid
Weight Loss60/40Carnitine, Green Tea Extract, Capsaicinoids
Diabetes70/30Ceylon Cinnamon, Chromium, Vanadium, Berberine
Fasting65/35Electrolytes, L-Leucine, HMB

goBHB® Pet — D:L Ratio 90/10

goBHB Pet reflects a highly conservative approach, emphasizing the naturally occurring D-BHB enantiomer, which is critical for energy metabolism in animals. D-BHB is naturally produced in animals during periods of fasting or ketosis, making it a safe and efficient energy substrate.


goBHB® Gaming — D:L Ratio 70/30

goBHB Gaming emphasizes sustained energy production to support prolonged focus and mental stamina required during intense gaming sessions. D-BHB fuels cognitive functions by enhancing mitochondrial efficiency and dopamine production, which are critical for sustained attention and reaction times. The L-BHB supports neurotransmitter balance, reducing stress and maintaining emotional stability under competitive conditions.


goBHB® Keto — D:L Ratio 80/20

goBHB Keto aligns with the ketogenic state’s emphasis on D-BHB as the primary energy substrate replacing glucose. D-BHB efficiently supports mitochondrial ATP production, sustaining energy levels and fueling metabolic processes during ketosis. The smaller inclusion of L-BHB provides complementary benefits, such as mild neuroprotection and anti-inflammatory effects.