Category: In The News

A new frontier in sports nutrition is emerging with the concept of “dual fuel” supplementation — combining carbohydrates with exogenous ketones to enhance athletic performance. Traditionally, athletes have relied on carbohydrates to replenish glycogen stores during intense activity. However, new research shows that pairing carbs with ketone bodies, such as beta-hydroxybutyrate (BHB), may extend endurance, reduce glycogen depletion, and provide a more stable energy supply by allowing the body to burn both glucose and ketones simultaneously.

Beyond performance enhancement, the dual fuel approach offers promising physiological benefits. These include reduced lactate production, improved cognitive clarity, and better post-exercise recovery. With supplements like goBHB making this strategy more accessible, athletes and fitness enthusiasts may soon adopt this metabolic synergy as a standard tool for optimizing both energy output and recovery in high-intensity and endurance sports.
(Source: PricePlow Blog)

The energy drink category has become absolutely loaded these past couple of years, thanks to established names expanding further, closely related brands expanding into the space, and newcomers trying their hand at the industry. The beverage we have in the spotlight here is certainly not one we saw coming, primarily due to the company behind it being so distant with REV7, a diverse, functional energy drink from the pillow manufacturer MyPillow.

Evening workouts often pose a challenge: the need for energy and focus without the sleep disturbances caused by traditional stimulant-based pre-workouts. While many stimulant-free options exist, they frequently lack effective energy-boosting components. goBHB, a form of beta-hydroxybutyrate, offers a solution by providing direct cellular energy through ATP production, enhancing both performance and sleep quality.

PricePlow proposes two hypothetical goBHB-powered pre-workout formulations tailored for evening trainers. The first is a realistic, cost-effective blend featuring goBHB, L-citrulline, beta-alanine, creatine monohydrate, and cognitive enhancers like L-tyrosine and citicoline. The second is a full-power version that pushes the boundaries of stimulant-free performance. These concepts aim to inspire brands to develop effective, stimulant-free pre-workouts that support both energy and recovery for those who train later in the day.

Source: blog.priceplow.com/formulators-corner/gobhb-stim-free-preworkouts

Study Goal

Researchers wanted to see how β-hydroxybutyrate (β-HB)—a ketone body produced during ketosis—affects the energy powerhouses (mitochondria) in muscle cells.

🧪 What They Did

They tested β-HB in:

• Mouse muscle cells in a lab
• Rats fed a ketogenic diet

🧠 What They Found (In Simple Terms)

1. Better Mitochondrial Function
   Muscle cells treated with β-HB had:
   • More efficient energy production (better oxygen use)
   • Lower harmful byproducts like hydrogen peroxide (H₂O₂), which causes oxidative stress
2. Increased Cell Survival
   Cells exposed to β-HB were healthier and more viable, showing better growth.
3. Less Mitochondrial Fragmentation
   β-HB encouraged mitochondria to stay connected (fusion) instead of breaking apart (fission), which is good for cell health.
4. Reduced Harmful Fat Molecules (Ceramides)
   These ceramides can hurt mitochondria and insulin sensitivity.
   β-HB lowered ceramide levels, possibly explaining the better mitochondrial structure and function.
5. Ketogenic Diet in Rats Had Similar Effects
   Rats fed a ketogenic diet had:
   • Lower body weight (without losing muscle)
   • Better mitochondrial respiration
   • Less oxidative stress in muscle cells
   • A trend toward less mitochondrial fragmentation

📌 Bottom Line

β-Hydroxybutyrate helps make muscle cells healthier by:

• Boosting mitochondrial efficiency
• Reducing oxidative stress
• Preventing cellular damage
• Supporting overall muscle cell survival

These benefits may help explain why ketogenic diets can maintain or even improve muscle function, despite having low carbohydrate intake.

🐁 The Mice (C2C12 Myotubes – Muscle Cells in Lab Culture)

The mice were not given a ketogenic diet.

Instead, their muscle cells (C2C12 myotubes) were:

• Cultured in a lab dish
• And directly treated with β-hydroxybutyrate (β-HB) at a concentration of 5 mM for 24 to 48 hours

This means:

• The β-HB was added directly to the cell medium, not through diet.
• The goal was to isolate the direct effects of β-HB on the mitochondria and cell viability without dietary variables.

Brigham Young University made history at the 2024 NCAA Cross Country Championships by winning both the men’s and women’s titles—an achievement fueled in part by goBHB ketone supplementation. As athletes pushed the limits of endurance, focus, and recovery, goBHB emerged as a key factor behind their peak performance, signaling a new chapter in sports nutrition and competitive training.

What if everything you’ve heard about the keto diet is only half the story?

Dr. Benjamin Bikman reveals the real science behind ketosis and insulin sensitivity and why going keto can transform your body in ways most people don’t understand. From preserving muscle to boosting brain function and gut health, this clip cuts through the hype and delivers the truth about how keto really works—and when it might not.

The energy drink category has become absolutely loaded these past couple of years, thanks to established names expanding further, closely related brands expanding into the space, and newcomers trying their hand at the industry. The beverage we have in the spotlight here is certainly not one we saw coming, primarily due to the company behind it being so distant with REV7, a diverse, functional energy drink from the pillow manufacturer MyPillow.

Read Full Article

The energy drink market has long been dominated by caffeine-based products, which, while effective, often lead to undesirable side effects like sleep disturbances and energy crashes. Beta-hydroxybutyrate (BHB), a ketone body, offers a clean and sustained energy source without the drawbacks of traditional stimulants. It provides actual cellular energy by directly fueling the mitochondria, bypassing the need for glucose and avoiding overstimulation.

Beyond its energy-boosting capabilities, BHB has been shown to improve sleep quality, making it an ideal ingredient for evening consumption. This positions BHB as a game-changer in the functional beverage industry, catering to consumers seeking effective, stimulant-free energy solutions. With its dual benefits of enhancing both energy and sleep, BHB is poised to redefine the landscape of energy drinks and functional beverages.

Source: blog.priceplow.com/energy-drinks/stimulant-free-bhb

30% of people who work out do so after 6 PM—the worst time to take a caffeinated pre-workout.

Now, you can fuel your evening workouts with a BHB-powered pre-workout that delivers energy without caffeine. When combined with glucose, it provides a dual-fuel effect for peak performance. Plus, BHB supports better sleep and reduced inflammation, so you wake up refreshed and soreness-free.

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New Study Revealed

Last week we teased the latest study, now we’re excited to share the full results. A randomized, double-blind, placebo-controlled trial has confirmed that daily intake of D-BHB significantly improves sleep quality in healthy adults.

Key Findings

• Better Mornings
  Reduced sleepiness upon waking
• Improved Sleep Patterns
  Enhanced sleep initiation and maintenance
• Refreshed Wake Ups
  Higher scores for feeling rejuvenated in the morning

This study marks a pivotal step in understanding how D-BHB supports better rest, recovery, and overall wellness.

📄 Read the Study

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Ready to explore the benefits of D-BHB?

🔗 Learn More

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