How goBHB Improves Brain Speed and Focus

How gobhb improves brain speed and focus

Enhance Mental Performance: BHB Cognitive Benefits

Optimizing cognitive performance has never been more critical. For students, gamers, and busy professionals, maintaining sharp focus and rapid brain function is essential. Exogenous ketones—specifically goBHB®—deliver significant BHB cognitive benefits, improving brain speed and focus by as much as 10%.

How BHB Boosts Brain Speed by 10%

Clinical research demonstrates that supplementation with goBHB can enhance brain processing speed by approximately 10%. This measurable improvement provides a tangible edge in scenarios where rapid thinking and decision-making matter most.

Who Benefits Most from goBHB?

  • Students: Accelerate learning and improve memory retention, aiding study sessions and exam performance.
  • Gamers: Boost reaction time and sharpen mental clarity, gaining a critical edge in competitive gaming scenarios.
  • Professionals: Enhance productivity, decision-making speed, and reduce mental fatigue during demanding workdays.

The Mechanism Behind BHB’s Cognitive Benefits

BHB (beta-hydroxybutyrate) is a powerful, efficient fuel for the brain, crossing the blood-brain barrier effortlessly and directly energizing neurons. Unlike stimulants like caffeine, BHB provides clean and sustained energy at the cellular level, optimizing cognitive performance without jitters or crashes.

Key mechanisms include:

  • Enhanced ATP Production: BHB produces more ATP—the brain’s primary energy source—than glucose, fueling neurons for faster cognitive processing.
  • Increased BDNF Levels: Stimulates Brain-Derived Neurotrophic Factor, improving learning, memory, and overall neuroplasticity.
  • Reduced Mental Fatigue: Provides consistent brain fuel, preventing energy dips that negatively impact cognitive function.
Clinical evidence supporting gobhb’s cognitive advantage

Clinical Evidence Supporting goBHB’s Cognitive Advantage

Numerous studies confirm the BHB cognitive benefits:

  • Reaction Time Improvement: Supplementation with goBHB resulted in measurable enhancements in cognitive reaction speed, achieving approximately 10% faster response times in cognitive tests.
  • Reduced Mental Fatigue: Participants reported sustained mental clarity and reduced cognitive fatigue, enabling longer, productive work or gaming sessions.
  • Memory and Learning: Increased hippocampal activity associated with memory improvement, aiding both short-term and long-term cognitive tasks.

Why goBHB Outperforms Traditional Cognitive Enhancers

goBHB offers distinct advantages over traditional cognitive supplements or stimulants:

BenefitgoBHBCaffeineNootropics
Brain Speed Improvement✅ (10%)✅ (Variable)✅ (Variable)
No Energy Crashes✅ (Varies)
Clean, Sustainable Energy✅ (Varies)
Direct ATP Generation
Reduced Oxidative Stress

Incorporating goBHB into Your Routine

Integrating goBHB into your daily regimen is straightforward:

  • Students: Take prior to studying or exams for enhanced mental clarity and improved recall.
  • Gamers: Supplement 20-30 minutes before sessions to maximize reaction speed and cognitive stamina.
  • Professionals: Use goBHB consistently to maintain sharpness and productivity throughout the workday, avoiding mid-day cognitive slumps.

Experience the goBHB Cognitive Advantage

The benefits of goBHB extend beyond mere supplementation—it’s a powerful cognitive optimizer capable of significantly enhancing brain speed, clarity, and focus. With a clinically demonstrated 10% improvement in brain speed, goBHB stands out as an ideal solution for students, gamers, and professionals committed to cognitive excellence.

Unlock your brain’s full potential with goBHB.


Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

BHB vs. Glucose: 225% More Cellular ATP

Bhb vs. glucose 225% more cellular atp ketone labs best bhb 001

Why BHB Outperforms Glucose in Cellular Energy Efficiency

Beta-hydroxybutyrate (BHB) is rapidly becoming recognized as the superior energy molecule compared to glucose. Emerging research reveals that BHB generates an impressive 225% more energy at the cellular level, positioning it as the most efficient cellular fuel available today.

Understanding Cellular ATP: The Real Energy Currency

Cells depend on ATP (adenosine triphosphate) as their primary energy currency. Both glucose and BHB ultimately convert into ATP, but the efficiency of these metabolic pathways differs significantly. BHB’s unique metabolic properties enable cells to produce substantially more ATP per unit oxygen compared to glucose.

The Science Behind the 225% Advantage

Research demonstrates that BHB produces approximately 2.25 times (225%) more ATP per molecule of oxygen consumed than glucose. This remarkable efficiency stems from BHB’s optimized metabolic pathway within mitochondria, generating high energy yields with significantly lower oxidative stress and fewer harmful metabolic byproducts.

  • Glucose: Inefficient, generates more reactive oxygen species (ROS), contributing to cellular aging and metabolic diseases.
  • BHB: High-efficiency metabolism, dramatically fewer ROS, supporting longevity, metabolic health, and improved physical performance.

Benefits of BHB’s Enhanced ATP Production

Leveraging the 225% greater energy efficiency of BHB has multiple physiological benefits:

  • Improved Cognitive Performance: Brain cells preferentially use BHB, enhancing clarity, focus, memory, and neuroplasticity.
  • Superior Athletic Endurance: Muscles fueled by BHB sustain peak performance longer, recover faster, and experience reduced fatigue.
  • Metabolic Health: Efficient ATP production reduces insulin dependency, stabilizing blood sugar and supporting weight management.
Clinical evidence supporting bhb superiority

Clinical Evidence Supporting BHB Superiority

Recent studies confirm BHB’s significant advantages:

  • ATP Yield: Clinical research reveals that BHB metabolism consistently outpaces glucose, delivering more ATP while simultaneously lowering oxidative stress markers.
  • Reduced Oxidative Stress: BHB generates 46 times fewer ROS compared to glucose metabolism, significantly reducing cellular aging and damage.
  • Enhanced Cellular Longevity: Improved mitochondrial efficiency directly correlates with enhanced lifespan and reduced risk of chronic diseases.

Why Cellular Efficiency Matters for Long-term Health

The shift to BHB as a primary cellular fuel represents a paradigm shift in nutrition and metabolism. Glucose, once considered the body’s preferred energy, is increasingly viewed as a metabolic burden due to its inefficient energy conversion and harmful byproducts. In contrast, BHB emerges as the ideal energy source, naturally optimized for maximum cellular ATP production and minimal oxidative stress.

Harnessing the Power of 225% Greater Energy Efficiency

By adopting BHB as the primary energy molecule, individuals can unlock unprecedented cellular efficiency. With its powerful 225% ATP advantage over glucose, BHB positions itself as the ideal choice for optimal metabolic health, performance, and longevity.

Embracing BHB represents more than a nutritional choice—it’s a critical investment in cellular health and energy optimization.


Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

What Is goBHB? Full Guide to Exogenous BHB

What is gobhb full guide to exogenous bhb ketone labs gobhb ketones 001

Introduction to goBHB

Beta-Hydroxybutyrate (BHB) is a naturally occurring ketone body, a potent cellular fuel traditionally produced by the liver during states of fasting, carbohydrate restriction, or ketogenic diets. goBHB® by Ketone Labs is a patented, high-quality exogenous form of BHB. Unlike endogenous ketones, goBHB provides immediate and accessible ketones without the dietary challenges of sustained ketosis.

Understanding the Molecule BHB

BHB is one of the three main ketone bodies—alongside acetoacetate (AcAc) and acetone—that serve as alternative energy sources for the brain, heart, and skeletal muscles during periods of glucose scarcity. BHB is uniquely efficient: it rapidly crosses the blood-brain barrier, accumulating in brain tissue, and provides significantly more energy per molecule compared to glucose.

How goBHB Works in the Body

goBHB supplementation delivers exogenous ketones that can immediately elevate blood ketone levels. These ketones bypass the traditional ketogenic pathway (fat oxidation in the liver) and directly provide the body and brain with a clean and efficient energy source. Unlike glucose, goBHB metabolism generates minimal reactive oxygen species (ROS), reducing oxidative stress and inflammation at the cellular level.

goBHB vs. Glucose: Superior Cellular Fuel

goBHB offers several metabolic advantages compared to glucose:

Gobhb vs glucose bhb superior cellular fuel 001
  • Efficiency: Produces ATP (adenosine triphosphate), the body’s primary energy currency, more efficiently than glucose per unit of oxygen consumed.
  • Reduced Oxidative Stress: Metabolism of BHB generates 46 times fewer harmful ROS compared to glucose, reducing cellular damage.
  • Independent of Insulin: Unlike glucose, BHB does not require insulin to enter cells, making it an ideal energy source for metabolic health.

Key Benefits of goBHB

goBHB supplementation provides a variety of well-documented health and performance benefits:

Cellular Energy and Metabolic Efficiency

  • Immediate and sustained energy for mental clarity and physical endurance.
  • Enhanced mitochondrial ATP production with less oxidative stress.

Cognitive Enhancement

  • Improves working memory, executive function, and overall brain performance.
  • Stimulates brain-derived neurotrophic factor (BDNF), promoting neuronal health and plasticity.

Metabolic Health

  • Supports insulin sensitivity, regulates blood sugar, and aids in weight management through appetite suppression and enhanced fat burning.

Athletic Performance

  • Extends physical endurance and accelerates recovery by providing an efficient and clean energy source without the spikes and crashes associated with glucose or caffeine-based supplements.

Hydration and Electrolyte Balance

  • goBHB electrolytes promote superior hydration by regulating fluid balance and enhancing electrolyte absorption, beneficial for athletic recovery and overall wellness.

Stress and Anxiety Reduction

  • Reduces normal stress and anxiety levels by modulating neurotransmitter pathways and mitigating the physiological effects of chronic stress.

Sleep Quality and Recovery

Emerging research also links BHB supplementation to improved sleep. Studies suggest that elevated ketone levels can enhance deep sleep stages by modulating GABAergic activity and reducing nighttime cortisol levels. 

Users report better sleep efficiency, fewer mid-night awakenings, and improved morning alertness when supplementing with goBHB—especially when taken in the evening alongside balanced electrolytes. This makes goBHB a practical tool for recovery, circadian alignment, and overall sleep hygiene.

Clinical Evidence and Efficacy

Research consistently supports goBHB’s effectiveness:

  • Weight Management: Clinical trials show that daily supplementation with goBHB can significantly reduce waist circumference and improve body composition without dietary restrictions.
  • Improved Cognition: Studies reveal that BHB supplementation enhances cognitive performance and reduces anxiety, improving quality of life metrics.
  • Metabolic Biomarkers: Evidence indicates that goBHB improves insulin sensitivity, reduces LDL cholesterol, and supports healthy blood glucose management.

Why Choose Exogenous Ketones?

Maintaining ketosis through dietary means can be difficult. goBHB provides a practical alternative, allowing individuals to access the benefits of ketones without the strict adherence required by ketogenic diets or fasting protocols. Exogenous ketones also enable precise dosing and timing, optimizing metabolic health, cognitive performance, and athletic recovery when it matters most.

goBHB as the Fourth Macronutrient

Emerging scientific literature positions BHB as the “fourth macronutrient” alongside carbohydrates, fats, and proteins. BHB provides direct, efficient ATP generation, making it uniquely valuable for cellular metabolism and overall health. This perspective underscores goBHB’s role not merely as a dietary supplement but as a fundamental nutrient supporting long-term metabolic flexibility and energy homeostasis.

Conclusion

goBHB by Ketone Labs is more than just a supplement—it represents a fundamental shift in how we view energy metabolism. With its unmatched efficiency, cognitive enhancement properties, and wide-ranging metabolic benefits, goBHB sets a new standard for cellular fuel. Whether optimizing physical performance, improving metabolic health, or enhancing cognitive function, goBHB offers scientifically validated results.


Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Ketone Labs Partners with Simpson Labs: A Game-Changing Alliance for goBHB Innovation​

Ketone labs & simpson labs partnership

Ketone Labs Partners with Simpson Labs: A Game-Changing Alliance for goBHB Innovation

Img 8324

By: Marc Lobliner, President – Ketone Labs

This past week marked a major milestone in the future of exogenous ketones and premium supplementation. I had the pleasure of visiting Simpson Labs in Valencia, California, alongside our Account Executive, David Barnes. We spent the day collaborating with industry veterans Donald Grace and Eric Simpson, diving deep into formulation strategy, application potential, and manufacturing capabilities.

We capped the day with a Dodgers game—and while the home team didn’t pull off the win, the real victory came in the form of a powerful new partnership that will benefit dozens of brands looking to bring cutting-edge, goBHB-powered formulas to life.

 

Simpson Labs has long been recognized as a gold standard in contract manufacturing. From powders to capsules to stick packs, they deliver world-class products backed by rigorous quality control and unmatched customer service. Their commitment to innovation and transparency aligns perfectly with our mission at Ketone Labs.

Img 8346

Through this collaboration, Simpson Labs will gain priority access to goBHB®—the most versatile and clinically validated exogenous ketone on the market. This positions them to offer their clients superior fat-burning, cognitive-enhancing, and endurance-boosting formulas that meet the rising demand for real, research-backed ingredients.

At Ketone Labs, we’re more than just an ingredient supplier—we’re your partner in building brands that perform. With Simpson Labs on board, our ability to support brands from ideation to finished product just got even stronger.

 

Stay tuned. The goBHB wave is only getting bigger—and with Simpson Labs in our corner, we’re ready to take it to the next level.

The Ultimate Ketone Breakdown with Dr. Ben Bikman and Marc Lobliner

Thumbnail 8

  • The Ultimate Ketone Breakdown with Dr. Ben Bikman and Marc Lobliner

By Marc Lobliner, IFBB Pro

I’ve talked about ketones for years—but this podcast with Dr. Ben Bikman dives deep into the real science behind why ketones aren’t just another fitness buzzword. They’re a biological fuel source your body was designed to use. And if you’re not tapping into that power, you’re leaving performance, clarity, and longevity on the table.

Let’s break it down.

 


Glucose vs. Ketones: What Fuels You Best?

Most of us are running on sugar—glucose. But your body was made to run more efficiently on ketones, especially beta-hydroxybutyrate (BHB). Dr. Bikman explains that while glucose spikes insulin and can drive inflammation, ketones are clean fuel. They don’t trigger insulin, and they help the body become metabolically flexible—able to switch between fat and glucose for energy.

Why does this matter? Because high insulin isn’t just about diabetes. It’s about brain fog, fat gain, and chronic disease. According to Bikman, over 93% of Americans have some form of metabolic dysfunction, often driven by constant carb fueling.


Ketones and Brain Power

This one hit home. Dr. Bikman shared how the brain prefers ketones over glucose in many scenarios, especially under stress or during fasting. In studies, BHB improves mental clarity, memory recall, and even mood.

There’s a reason Alzheimer’s is being called Type 3 Diabetes—it’s rooted in insulin resistance in the brain. Ketones bypass that broken system and deliver the energy your neurons need.

Dr. Bikman cited research showing ketones increase BDNF (Brain-Derived Neurotrophic Factor), which supports learning, memory, and even neuroprotection. In short: ketones help your brain stay sharp and protected against aging.


BHB: The Body’s Super Fuel

BHB is more than just an energy molecule—it’s a signaling molecule. That means it tells your body to do things like:

  • Reduce inflammation (by blocking the NLRP3 inflammasome)

  • Burn more fat

  • Boost mitochondrial function

  • Improve muscle preservation during caloric deficits or fasting

Dr. Bikman emphasized that BHB works independent of diet. You don’t have to go strict keto to see benefits—exogenous ketones can raise BHB levels in your blood within 30 minutes and start shifting your metabolism toward fat oxidation.


Performance and Recovery: Ketones in the Gym

I’ve personally seen the benefits of using ketones in training. What Dr. Bikman explains is that ketones provide a stable, long-burning fuel that doesn’t crash. That means more consistent energy during lifts, endurance sessions, and even during tournaments or long competitions.

Research cited in the podcast shows that ketone supplementation improved recovery markers, reduced perceived exertion, and preserved lean muscle mass during cut phases.


Ketones and Longevity

One of the most exciting parts of this conversation was the longevity angle. Elevated ketones are associated with increased autophagy (cellular cleanup), reduced oxidative stress, and better insulin sensitivity—all markers of extended lifespan.

As Dr. Bikman pointed out, some of the longest-living populations in the world regularly undergo periods of fasting or carbohydrate restriction—naturally raising ketone levels.


Why goBHB Matters

Not all ketones are created equal. goBHB® is the gold standard for exogenous ketones—it’s bioidentical, clinically studied, and fast-acting. You can find it in products ranging from fat burners to brain health to endurance support.

It’s what I trust in my own supplement stack and in formulas we develop, because the science is there—and people feel the difference.


Final Thoughts

We’re only scratching the surface of what ketones can do. Whether your goal is fat loss, brain power, or living longer and stronger—ketones are the missing link most people are ignoring.

You don’t need to go zero-carb. You just need to use the fuel your body was built for.

Watch the full conversation with Dr. Ben Bikman here: https://youtu.be/TywW4F1cRbg

 

If you want to feel the difference, try a product with goBHB and track your energy, focus, and recovery. You’ll never go back.

BDNF: The Master Switch for Brain Health

 

THE WORLD’S MOST POWERFUL SCIENCE BACKED INGREDIENT.

BDNF (Brain-Derived Neurotrophic Factor) is one of the most powerful molecules in the human body. It is the master growth factor that controls brain development, repair, resilience, and performance. High levels of BDNF are associated with:

  • Enhanced memory and learning
  • Improved mood and emotional balance
  • Faster recovery from brain injuries
  • Protection from neurodegenerative diseases (Alzheimer’s, Parkinson’s, ALS)
  • Increased metabolic flexibility
  • Reduced inflammation and oxidative stress
  • Prevention of age-related cognitive decline

The BDNF Crisis: A Modern Epidemic

  • After age 40, BDNF levels naturally decline.
  • Chronic stress, poor diet, lack of exercise, inflammation, and poor sleep all accelerate this drop.
  • Low BDNF levels are now strongly linked to the global rise in dementia, mood disorders, obesity, and brain aging.

BHB: The Most Powerful Natural BDNF Activator

BHB (Beta-Hydroxybutyrate) is the primary and most powerful ketone body.

Multiple published studies have shown BHB activates BDNF through six distinct and complementary biological mechanisms:

1. Epigenetic Activation via HDAC Inhibition

  • BHB inhibits Class I histone deacetylases (HDACs), unlocking gene transcription for BDNF.
  • This is the most direct known dietary method to increase BDNF at the genetic level.

2. Powerful Anti-Inflammatory Effect

  • BHB suppresses key inflammatory cytokines (IL-1β, IL-6, TNF-alpha).
  • Chronic inflammation suppresses BDNF. BHB reverses this, allowing BDNF expression to rise.

3. Oxidative Stress Reduction

  • BHB scavenges damaging reactive oxygen species (ROS).
  • Reducing oxidative stress protects neurons and allows optimal BDNF production.

4. Neuronal Energy Optimization

  • BHB provides a clean, efficient fuel source for brain mitochondria.
  • Supports ATP production needed for BDNF-driven neuroplasticity.

5. Sleep Enhancement

  • BHB supports deep slow-wave sleep cycles, directly linked to BDNF upregulation.
  • Better sleep = higher natural BDNF output.

6. Synergy with Exercise (HIIT)

  • HIIT dramatically increases BDNF.
  • BHB supplementation amplifies this effect by enhancing recovery, reducing post-exercise inflammation, and maintaining elevated BDNF for longer.

BHB + BDNF: The Neuroprotection Stack

Because BHB impacts BDNF through multiple pathways simultaneously, it may offer unmatched neuroprotection and cognitive enhancement. Studies suggest BHB may:

  • Improve working memory and learning speed
  • Reduce anxiety and depression symptoms
  • Lower risk of Alzheimer’s disease by improving amyloid clearance
  • Protect neurons from age-related degeneration
  • Improve insulin sensitivity and metabolic brain health
  • Support mood stability and emotional resilience
  • Increase longevity of brain function well into advanced age

Clinical Literature Supporting BHB’s BDNF Activation

  • Sleiman SF et al. BHB activates BDNF expression via class I HDAC inhibition. Nature Communications, 2016.
  • Rahman M et al. BHB as a neuroprotective metabolite in oxidative stress. J Cell Biochem, 2014.
  • Kanoski SE et al. BDNF, obesity, and cognition. Physiol Behav, 2011.
  • Gomez-Pinilla F et al. Exercise, BDNF and cognitive function. Nat Rev Neurosci, 2008.
  • Newman JC, Verdin E. Ketone bodies as signaling metabolites. Cell Metabolism, 2014.

The Bottom Line

“BHB is one of the most effective, scientifically-validated compounds for naturally increasing BDNF. No other nutrient activates this many BDNF pathways simultaneously.”

For individuals concerned with cognitive health, mood stability, neuroprotection, and brain longevity, BHB offers a uniquely powerful solution.

BHB fuels the brain. BDNF builds the brain. Together, they unlock your brain’s full potential.

Why BDNF Matters?

Why bdnf matters

HOW BHB INCREASES BDNF

How bhb increases bdnf

THE CRISIS: BDNF DECLINES WITH AGE, STRESS, AND INFLAMMATION

Bdnf
  • BDNF levels naturally fall after age 40
  • Obesity, high sugar diets, poor sleep and chronic inflammation reduce BDNF
  • Modern lifestyle leads to epidemic levels of low BDNF, cognitive decline, and mood disorders

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

This Molecule Can Change Your Life | Podcast with Dr. Ben Bikman & Marc Lobliner

Tyww4f1crbg hd

In this powerful episode, Dr. Ben Bikman joins Marc Lobliner to uncover the science behind one of the most overlooked yet life-changing molecules: beta-hydroxybutyrate (BHB). You’ll learn:

✅ What BHB actually is and how it fuels your brain and body
✅ Why ketones like goBHB are more than just a “keto supplement”
✅ How BHB impacts metabolism, energy, inflammation, and longevity
✅ The shocking truth about glucose, insulin resistance, and modern health
✅ How YOU can take control of your health using cutting-edge science

Whether you’re a high-performing athlete, biohacker, or just trying to feel better every day—this episode is for you.

Therapeutic Ketosis for Heart Failure

Chatgpt image jul 11, 2025, 10 18 05 am

Therapeutic Ketosis for Heart Failure

By: Marc Lobliner, IFBB Pro

A recent state‑of‑the‑art review published in the Journal of Cardiac Failure (Kodur et al., 2025) shows that failing hearts naturally increase ketone oxidation as a survival mechanism for energy production. Small clinical trials have demonstrated that supplementing with ketones like beta-hydroxybutyrate (BHB) can improve heart function in patients with heart failure. The review highlights promising results for exogenous ketones in boosting cardiac output, stroke volume, and ejection fraction—metrics directly tied to heart performance.


Key Insights from the Review

Failing hearts suffer from an energy crisis. Normally, the heart burns glucose and fatty acids. But in heart failure, those pathways become inefficient. As a result, the heart shifts toward burning ketones, which are a more efficient and clean fuel.

The most accessible and impactful ketone for this purpose is beta-hydroxybutyrate (BHB). Studies now show that even in the most compromised hearts, infusions of BHB lead to immediate improvements in pumping capacity, oxygen use, and energy output.

These trials show that therapeutic ketosis—whether induced via diet or supplementation—can play a major role in improving cardiac performance.


Additional Clinical and Mechanistic Evidence

Acute Hemodynamic Boost
Research demonstrates that infusion of 3-OHB in heart failure patients led to a 40% increase in cardiac output, a 20 mL improvement in stroke volume, and an 8% increase in ejection fraction. This was achieved without a loss in cardiac efficiency or increased oxygen demand.

Ketones as Preferred Fuel
In failing hearts, up to 16% of the energy production (ATP) can come from ketones. This shift in metabolism suggests that the heart prefers ketones when under stress, and providing them exogenously makes a real difference in performance.

Anti-Inflammatory and Remodeling Effects
BHB has been shown to inhibit the NLRP3 inflammasome—a driver of chronic inflammation and tissue scarring in heart failure. By reducing inflammation, BHB may also limit myocardial fibrosis and support cardiac remodeling.

Endothelial and Vascular Support
Ketones have demonstrated an ability to support endothelial cell growth and blood vessel formation, which may improve circulation and nutrient delivery to the heart muscle itself.

 

Alignment with SGLT-2 Inhibitor Research
SGLT-2 inhibitors like empagliflozin, known for improving heart failure outcomes, also raise ketone levels. Many researchers believe this increase in circulating BHB is one of the reasons behind their success.

Screenshot 2025 07 11 at 9.15.18 am

The Role of goBHB Supplementation

goBHB is a patented form of exogenous BHB that offers all the metabolic benefits of therapeutic ketosis—without needing a restrictive ketogenic diet. It rapidly elevates blood ketone levels into the 1 to 3 mM range, which mirrors what’s seen in the successful heart failure trials.

For individuals recovering from cardiovascular strain, dealing with heart failure symptoms, or simply looking to improve endurance and energy metabolism, goBHB offers a promising and accessible tool. It provides fuel, reduces inflammation, and may enhance the overall metabolic flexibility of the heart.


Take-Home Message

The new research—including the 2025 review by Kodur et al.—shows that goBHB isn’t just a performance supplement or keto hack. It’s a powerful metabolic fuel with clinically relevant benefits for cardiovascular health.

For patients with heart failure, BHB helps the heart recover some of its lost function. For athletes and high-performers, it can enhance endurance and recovery. For those looking to support long-term heart health, it offers an additional tool in the metabolic arsenal.

With its ability to improve cardiac energy efficiency, reduce inflammation, and support vascular integrity, goBHB stands at the forefront of the next wave of heart health support—grounded in clinical science, not hype.


References

 

  • Kodur et al., Therapeutic Ketosis for Heart Failure: A State-of-the-Art Review. Journal of Cardiac Failure, 2025. PubMed ID: 40043832

  • Nielsen et al., Hemodynamic Effects of Ketone Bodies in Heart Failure with Reduced Ejection Fraction. Circulation, 2019.

  • Matsuura et al., Ketones and the Heart: Metabolic Principles. Circulation Research, 2023.

  • Frontiers in Pharmacology: Beta-hydroxybutyrate and Heart Function, 2024.