By Marc Lobliner, IFBB Pro

Menopause is a major transition in a woman’s life. Declining estrogen and progesterone bring with them a range of symptoms: hot flashes, night sweats, mood swings, brain fog, weight gain, sleep disturbances, lower energy, and changes in metabolism. Finding solutions that address multiple of these symptoms is challenging. That’s where the ingredient goBHB® comes into play. goBHB® offers a novel ketone‑based approach that may help women navigate this transition with greater ease.

What is goBHB®

goBHB® is a proprietary form of exogenous beta‑hydroxybutyrate (BHB) designed to raise circulating ketone levels without requiring strict carbohydrate restriction or full ketogenic dieting. Research indicates that BHB is a preferred fuel source for the brain and other tissues, and may support metabolic health, appetite control, mitochondrial function, and inflammation modulation.

For women in menopause, the metabolic and cognitive stresses are intensified. Lower estrogen levels reduce insulin sensitivity, shift fat distribution, compromise mitochondrial efficiency, and increase systemic inflammation. The ability of BHB to support energy metabolism and brain function makes goBHB® a tool worth evaluating in this context.

How goBHB® may address specific menopause‑related challenges

1. Energy and brain fog
As estrogen falls, many women report reduced mental clarity, slower reaction times, and more fatigue. BHB provides an alternative fuel substrate for the brain, bypassing some of the inefficiencies seen when glucose metabolism is disrupted. Studies show that exogenous ketone consumption elevates blood BHB and can improve brain metabolic markers.

By using goBHB® as part of a daily or targeted protocol, women may experience improved mental clarity, sharper focus, and more consistent energy—especially during times when hormonal shifts make those harder to maintain.

2. Weight management and body‑composition support
Menopause often brings fat gain, particularly around the abdomen, and loss of muscle mass. Insulin resistance is more common, which further complicates weight control. Research shows that ketone supplementation can acutely lower blood glucose and may support fat oxidation. 

Using goBHB® alongside a well‑structured nutrition and training program (ideally strength training to preserve lean mass) can provide a metabolic “nudge” for women dealing with the body‑composition challenges of menopause.

3. Appetite, cravings and insulin sensitivity
Hormonal shifts during menopause can increase hunger hormone ghrelin, fuel cravings, and destabilize blood sugar. A ketogenic lifestyle has been shown to reduce ghrelin spikes and stabilize appetite. 

Because goBHB® raises circulating ketones, even when not on a full ketogenic diet, it can assist in moderating appetite, reducing cravings for carbohydrate‑rich foods, and promoting better insulin sensitivity. Over time, this may help reduce episodes of instability that exacerbate menopausal symptoms such as hot flashes and night sweats.

4. Mood, sleep and inflammation
Menopause is associated with higher levels of systemic inflammation, poorer sleep quality, and mood disturbances. BHB has neuroprotective properties: it has been shown to increase brain‑derived neurotrophic factor (BDNF), promote synaptic plasticity, and regulate mitochondrial function. 

Integrating goBHB® may help create a more favorable brain and mitochondrial environment, contributing to improved mood stability, more restorative sleep, and reduced neuro‑inflammation which often underlies brain fog and fatigue.

Practical application and protocols

If you are advising women in menopause about goBHB®, here are considerations:

• Choose a high‑quality goBHB® product: MTS Nutrition offers a goBHB® formulation, and Cleanform Nutrition offers a goBHB® version as well. 

• Start with one serving daily, preferably in the morning or pre‑workout, to support energy and cognition. Additional serving might be taken later in the day if sleep support or cognitive boost is desired.

• Pair goBHB® with resistance training and a well‑balanced diet (adequate protein, healthy fats, low‑to‑moderate carbohydrates) to maximise fat‑loss and lean‑mass retention.

• Prioritise sleep hygiene, stress‑management, and omega‑3 fatty acid intake (for example from fish oil) since these amplify the benefits of BHB on inflammation and brain health.

• Monitor for changes in appetite, mood, sleep quality, body‑composition, and energy levels over a 6–8 week period. Adjust dosage or timing based on response.

Important caveats

It is essential to acknowledge that the research on BHB supplementation in menopausal women is still emergent. While there is strong mechanistic rationale and early clinical research showing benefits of BHB on metabolism, cognition, and appetite, there are no large‑scale, long‑term randomized controlled trials specifically in menopausal populations. 

Women who are on hormone replacement therapy, have thyroid issues, or other endocrine conditions should consult with their healthcare provider prior to starting any supplement. Additionally, this article does not replace personalized medical advice.

Final thoughts

 

Menopause is a complex phase with multifaceted challenges. A tool like goBHB® offers an innovative way to address several of those challenges simultaneously: energy, cognitive clarity, metabolic support, appetite regulation, and inflammation. When combined with strength training, proper nutrition, and sleep hygiene, goBHB® from MTS Nutrition or Cleanform Nutrition can become a strategic part of your menopause support plan.

While it is not a cure for menopause, it represents a meaningful option for those seeking to navigate this phase with greater resilience and vitality.